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In the higher standards of milk production, the priority in modern breeding is keeping dairy cows in high lactation and healthy. The proper analysis, as well as control. of their feeding and metabolic status is immensely important for the health condition of the herd. The disproportion between the genetically determined ability for milk production and the limitations in improving the energy value of the ration may be the cause of metabolic disorders. Negative energy balance has a major impact on the body's hormonal balance and organ functions and mostly appears during transition periods: from 3 to 2 weeks\n                    <jats:italic>prepartum<\/jats:italic>\n                    until 2\u20133 weeks\n                    <jats:italic>postpartum<\/jats:italic>\n                    . The term \u2018transition\u2019 is used to underscore the important physiological, metabolic and nutritional changes occurring in this time. The manner in which these changes occur and how they are diagnosed and detected are extremely important, as they are closely related to clinical and subclinical\n                    <jats:italic>postpartum<\/jats:italic>\n                    diseases, lactation and reproductive performance\u00a0\u2013\u00a0factors that significantly shape the profitability of production. Therefore the priority for intensive milk production is prevention of metabolic diseases and other disorders. It is the intent of this review to synthesize and summarize the information currently available on metabolic status and physiological changes in the cow's body that occur during lactation, as well as to discuss the interpretation of the results, which will be a useful diagnostic tool in nutritional evaluations of the dairy herd. \u00a9 2016 Society of Chemical Industry\n                  <\/jats:p>","DOI":"10.1002\/jsfa.7779","type":"journal-article","created":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T07:29:24Z","timestamp":1462087764000},"page":"4321-4328","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":131,"title":["Metabolic profiles of cow's blood; a review"],"prefix":"10.1002","volume":"96","author":[{"given":"Kamila","family":"Puppel","sequence":"first","affiliation":[{"name":"Cattle Breeding Division, Animal Breeding and Production Department Warsaw University of Life Sciences  Ciszewskiego 8 PL\u201002\u2010678 Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beata","family":"Kuczy\u0144ska","sequence":"additional","affiliation":[{"name":"Cattle Breeding Division, Animal Breeding and Production Department Warsaw University of Life Sciences  Ciszewskiego 8 PL\u201002\u2010678 Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,31]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"83","article-title":"Number of lactations affects metabolic profile of dairy cows","volume":"6","author":"Rossato W","year":"2001","journal-title":"Arch Vet Sci"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1751-0147-50-31"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022-0302(04)73446-3"},{"key":"e_1_2_10_5_1","volume-title":"Clinical Biochemistry of Domestic Animals","author":"Kaneko JJ","year":"2008"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.5900"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022-0302(06)72195-6"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022-0302(01)70204-4"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anifeedsci.2005.08.003"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1262\/jrd.1056S29"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022-0302(98)75657-7"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022-0302(02)74420-2"},{"key":"e_1_2_10_13_1","unstructured":"DrackleyJKandJanovick GuretzkyNA Controlled energy diets for dry cows.Proc. 8th Western Dairy Management Conf. 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