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Twelve Duroc \u00d7 Landrace \u00d7 Yorkshire male finisher pigs (60.7 \u00b1 1.9 kg), housed individually in open\u2010circuit respiration chambers, were randomly assigned to two dietary groups, namely basal diet (control) and basal diet supplemented with 1% (w\/w) inulin. At the end of the 45 day experiment, pigs were slaughtered and volatile fatty acid (<jats:styled-content style=\"fixed-case\">VFA<\/jats:styled-content>) concentration, sulfate radical (<jats:styled-content style=\"fixed-case\">SO<jats:sub>4<\/jats:sub><jats:sup>2<\/jats:sup><\/jats:styled-content><jats:sup>\u2212<\/jats:sup>) concentration, population of sulfate\u2010reducing bacteria (<jats:styled-content style=\"fixed-case\">SRB<\/jats:styled-content>) and expression of methionine gamma\u2010lyase (<jats:styled-content style=\"fixed-case\">MGL<\/jats:styled-content>) gene were determined in contents from the caecum, colon (two segments) and rectum. Metabonomic analysis was used to compare differences in biochemical composition, and the Illumina <jats:styled-content style=\"fixed-case\">MiSeq<\/jats:styled-content> procedure to investigate differences in bacterial components, in the different parts of the large intestine between inulin\u2010supplemented and inulin\u2010free (control) groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Inulin decreased (<jats:italic>P<\/jats:italic> &lt; 0.05) the average daily enteric <jats:styled-content style=\"fixed-case\">H<jats:sub>2<\/jats:sub>S<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CH<jats:sub>3<\/jats:sub>SH<\/jats:styled-content> production by 12.4 and 12.1% respectively. The concentrations of acetate, propionate and butyrate in the large intestinal content were significantly increased (<jats:italic>P<\/jats:italic> &lt; 0.05) with inulin treatment, whereas valerate concentration and <jats:styled-content style=\"fixed-case\">MGL mRNA<\/jats:styled-content> expression decreased (<jats:italic>P<\/jats:italic> &lt; 0.05). The growth of <jats:italic>Lactobacillus<\/jats:italic>, <jats:italic>Butyrivibrio<\/jats:italic>, <jats:italic>Pseudobutyrivibrio<\/jats:italic>, <jats:italic>Bifidobacterium<\/jats:italic> and <jats:italic>Clostridium butyricum<\/jats:italic> was stimulated, while that of <jats:italic>Desulfovibrio<\/jats:italic>, the dominant <jats:styled-content style=\"fixed-case\">SRB<\/jats:styled-content>, was inhibited, and there was an accumulation of <jats:styled-content style=\"fixed-case\">SO<jats:sub>4<\/jats:sub><jats:sup>2<\/jats:sup><\/jats:styled-content><jats:sup>\u2212<\/jats:sup> in the large intestinal content of the inulin\u2010supplemented pigs, suggesting that inulin mitigates <jats:styled-content style=\"fixed-case\">H<jats:sub>2<\/jats:sub>S<\/jats:styled-content> generation from the <jats:styled-content style=\"fixed-case\">SO<jats:sub>4<\/jats:sub><jats:sup>2<\/jats:sup><\/jats:styled-content><jats:sup>\u2212<\/jats:sup> reduction pathway by reducing the growth of <jats:styled-content style=\"fixed-case\">SRB<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>The results showed that inulin mitigates <jats:styled-content style=\"fixed-case\">CH<jats:sub>3<\/jats:sub>SH<\/jats:styled-content> generation via three methionine degradation metabolic pathways and <jats:styled-content style=\"fixed-case\">H<jats:sub>2<\/jats:sub>S<\/jats:styled-content> generation from two cysteine degradation metabolic pathways, thus resulting in increased synthesis of these two sulfur\u2010containing amino acids in the pig large intestine. \u00a9 2016 Society of Chemical Industry<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.8050","type":"journal-article","created":{"date-parts":[[2016,9,24]],"date-time":"2016-09-24T11:26:47Z","timestamp":1474716407000},"page":"2382-2391","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Efficacy and role of inulin in mitigation of enteric sulfur\u2010containing odor in pigs"],"prefix":"10.1002","volume":"97","author":[{"given":"Yuan\u2010Fan","family":"Deng","sequence":"first","affiliation":[{"name":"College of Animal Science South China Agricultural University  Guangzhou 510642 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan\u2010Yuan","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Animal Science South China Agricultural University  Guangzhou 510642 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi\u2010Tao","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Animal Science South China Agricultural University  Guangzhou 510642 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Animal Science South China Agricultural University  Guangzhou 510642 China"},{"name":"Key Laboratory of Tropical Agricultural Environment South China Agricultural University  Guangzhou China"},{"name":"Guangdong Enterprise Laboratory of Healthy Animal Husbandry and Environment Control  Xinxing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan\u2010Boo","family":"Liang","sequence":"additional","affiliation":[{"name":"Laboratory of Animal Production, Institute of Tropical Agriculture Universiti Putra Malaysia  Serdang 43400 Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Tufarelli","sequence":"additional","affiliation":[{"name":"Section of Veterinary Science and Animal Production, Department of Emergency and Organ Transplantation (DETO) University of Study of Bari \u2018Aldo Moro\u2019  I\u201070010 Valenzano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vito","family":"Laudadio","sequence":"additional","affiliation":[{"name":"Section of Veterinary Science and Animal Production, Department of Emergency 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