{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:49:19Z","timestamp":1786978159533,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,1,10]],"date-time":"2017-01-10T00:00:00Z","timestamp":1484006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004156","name":"Mahidol University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004156","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>\n                      Mixed larvae and pupae of weaver ant (\n                      <jats:italic>Oecophylla smaragdina<\/jats:italic>\n                      ) are widely used as an important food ingredient in regions of Thailand. They have high nutritional values and comprise 53% protein and 13% lipid. Peptides derived from food proteins have been shown to possess biological activities.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      Peptides derived from pepsin and trypsin digestion of these weaver ant larvae and pupae were purified based on angiotensin\u2010converting enzyme (\n                      <jats:styled-content style=\"fixed-case\">ACE<\/jats:styled-content>\n                      ) inhibitory and antioxidant activities, and their amino acid sequences were identified by liquid chromatography\u2013tandem mass spectrometry (\n                      <jats:styled-content style=\"fixed-case\">LC\u2010MS<\/jats:styled-content>\n                      \/\n                      <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content>\n                      ).\n                      <jats:italic>In silico<\/jats:italic>\n                      docking of peptides with\n                      <jats:styled-content style=\"fixed-case\">ACE<\/jats:styled-content>\n                      successfully predicted the inhibitory peptides as confirmed by their chemical synthesis. Two peptides with sequences of\n                      <jats:styled-content style=\"fixed-case\">FFGT<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">LSRVP<\/jats:styled-content>\n                      showed\n                      <jats:styled-content style=\"fixed-case\">\n                        IC\n                        <jats:sub>50<\/jats:sub>\n                      <\/jats:styled-content>\n                      values for\n                      <jats:styled-content style=\"fixed-case\">ACE<\/jats:styled-content>\n                      inhibition of 19.5 \u00b1 1.7 and 52.7 \u00b1 4.0 \u00b5mol L\n                      <jats:sup>\u22121<\/jats:sup>\n                      , respectively. In addition, one potent antioxidant peptide with a sequence of\n                      <jats:styled-content style=\"fixed-case\">CTKKHKPNC<\/jats:styled-content>\n                      showed\n                      <jats:styled-content style=\"fixed-case\">\n                        IC\n                        <jats:sub>50<\/jats:sub>\n                      <\/jats:styled-content>\n                      values of 48.2 \u00b1 2.1 \u00b5mol L\n                      <jats:sup>\u22121<\/jats:sup>\n                      for\n                      <jats:styled-content style=\"fixed-case\">DPPH<\/jats:styled-content>\n                      assay and 38.4 \u00b1 0.2 \u00b5mol L\n                      <jats:sup>\u22121<\/jats:sup>\n                      for\n                      <jats:styled-content style=\"fixed-case\">ABTS<\/jats:styled-content>\n                      assay, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>\n                      These results indicate that proteins from larvae and pupae of weaver ants are potential sources of peptides with anti\u2010\n                      <jats:styled-content style=\"fixed-case\">ACE<\/jats:styled-content>\n                      and antioxidation bioactivities. \u00a9 2016 Society of Chemical Industry\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jsfa.8155","type":"journal-article","created":{"date-parts":[[2016,11,23]],"date-time":"2016-11-23T21:46:52Z","timestamp":1479937612000},"page":"3133-3140","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Angiotensin\u2010converting enzyme inhibitory and antioxidant peptides from digestion of larvae and pupae of Asian weaver ant,\n                    <i>Oecophylla smaragdina<\/i>\n                    , Fabricius"],"prefix":"10.1002","volume":"97","author":[{"given":"Werawich","family":"Pattarayingsakul","sequence":"first","affiliation":[{"name":"Department of Biotechnology, Faculty of Science Mahidol University  Bangkok 10400 Thailand"},{"name":"Mahidol University\u00a0\u2013\u00a0Osaka University Collaborative Research Center for Bioscience and Biotechnology, Faculty of Science Mahidol University  Bangkok 10400 Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjaree","family":"Nilavongse","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, Faculty of Science Mahidol University  Bangkok 10400 Thailand"},{"name":"Mahidol University\u00a0\u2013\u00a0Osaka University Collaborative Research Center for Bioscience and Biotechnology, Faculty of Science Mahidol University  Bangkok 10400 Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onrapak","family":"Reamtong","sequence":"additional","affiliation":[{"name":"Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine Mahidol University  Bangkok 10400 Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamorn","family":"Chittavanich","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Science Mahidol University  Bangkok 10400 Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idsada","family":"Mungsantisuk","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, Faculty of Science Mahidol University  Bangkok 10400 Thailand"},{"name":"Mahidol University\u00a0\u2013\u00a0Osaka University Collaborative Research Center for Bioscience and Biotechnology, Faculty of Science Mahidol University  Bangkok 10400 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