{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T03:52:26Z","timestamp":1784001146141,"version":"3.55.0"},"reference-count":47,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,8,22]],"date-time":"2017-08-22T00:00:00Z","timestamp":1503360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"City of Scientific Research and Technologicals"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Aflatoxins (AFs) are a group of toxic, nephrotoxic, hepatotoxic and carcinogenic fungal metabolites. Heat\u2010 and acid\u2010treated yeasts, probiotic bacteria and their combination were used to remove AFB1, AFB2, AFG1 and AFG2 from human and animal food.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>The <jats:italic>in vitro<\/jats:italic> study revealed that the highest removal percentage of AFs in phosphate\u2010buffered saline was recorded after 72\u2009h with the yeast\u2013probiotic coctile, reaching 95.59%. Therefore, this coctile was added to Cerelac contaminated with AFB1, AFB2, AFG1 and AFG2, and the removal percentages were 8.17%, 36.12%, 44.75%, 64.72% and 93.21% after 6, 12, 24, 48 and 72\u2009h of treatment, respectively. Cerelac yeast\u2013probiotic coctile was administered to female rats and the results showed that all AFs (AFB1, AFB2, AFG1 and AFG2) were detected in the serum of mother rats for both AF groups III and IV. On the other hand, AFM1 and AFM2 metabolites were not observed in mothers' sera but were detected in all infants of groups III and IV. Meanwhile, AFB1, AFB2, AFG1 and AFG2 were not observed in infants' sera.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>A mixture of yeast\u2013probiotic coctile was successful in reducing the level of AF in rat sera and diminished the deleterious effect of AFs on animal health. \u00a9 2017 Society of Chemical Industry<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.8518","type":"journal-article","created":{"date-parts":[[2017,7,3]],"date-time":"2017-07-03T07:52:42Z","timestamp":1499068362000},"page":"707-718","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Supplementation of Cerelac baby food with yeast\u2013probiotic cocktail strains induces high potential for aflatoxin detoxification both <i>in vitro<\/i> and <i>in vivo<\/i> in mother and baby albino rats"],"prefix":"10.1002","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8910-4038","authenticated-orcid":false,"given":"Gamal M","family":"Hamad","sequence":"first","affiliation":[{"name":"Food Technology Department Arid Land Cultivation Research Institute (ALCRI), City of Scientific Research and Technology Applications (SRTA\u2010 CITY), New Borg El\u2010Arab City  Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarek H","family":"Taha","sequence":"additional","affiliation":[{"name":"Environmental Biotechnology Department Genetic Engineering and Biotechnology Research Institute (GEBRI), City of Scientific Research and Technology Applications (SRTA\u2010 CITY), New Borg El\u2010Arab City  Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsayed E","family":"Hafez","sequence":"additional","affiliation":[{"name":"Plant Protection and Biomolecular Diagnosis Department Arid Land Cultivation Research 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