{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T03:46:35Z","timestamp":1790048795360,"version":"4.0.1"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T00:00:00Z","timestamp":1542672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Anhui Natural Sciences Foundation","award":["11008761"],"award-info":[{"award-number":["11008761"]}]},{"name":"Anhui Sciences and Technology Plant Project","award":["1704a07020098"],"award-info":[{"award-number":["1704a07020098"]}]},{"name":"Anhui Sciences and Technology Plant Project","award":["Ilj20170144"],"award-info":[{"award-number":["Ilj20170144"]}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2019,3,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Wheat bran has been shown to have health\u2010promoting benefits in relation to diabetes, colorectal cancer, cardiovascular disease, constipation, irritable bowel syndrome, diverticulitis, and gastrointestinal disease. However, its effects on obesity, hyperglycemia, hepatotoxicity, and hyperlipidemia are not yet clear. The effects of the consumption of wheat bran of different particle sizes (coarse, 427.55 \u00b5m versus ultra\u2010fine, 11.63 \u00b5m) on body weight, serum glucose, liver, and blood lipid metabolism levels in high\u2010fat\u2010diet induced rats fed for 5 weeks were investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>The high\u2010fat diet significantly increased body weight, serum glucose, serum and liver lipids, and malondialdehyde levels. However, addition of coarse and ultra\u2010fine wheat bran to a high\u2010fat diet decreased weight gain, reduced the levels of serum and liver total cholesterol, triglycerides, malondialdehyde, serum low\u2010density lipoprotein, and serum glucose, and improved serum high\u2010density lipoprotein. Moreover, when two particle sizes were compared, the highest impact was exhibited by the wheat bran containing the larger particle size.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>The results suggest that micronized wheat bran significantly improves anti\u2010hyperlipidemic and hepatoprotective properties that might provide a safeguard to protect humans against metabolic syndrome abnormalities and other acute, recurrent, or chronic diseases. \u00a9 2018 Society of Chemical Industry<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.9397","type":"journal-article","created":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T03:09:51Z","timestamp":1538363391000},"page":"1990-1996","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Anti\u2010hyperlipidemic and hepatoprotective properties of wheat bran with different particle sizes"],"prefix":"10.1002","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6552-6626","authenticated-orcid":false,"given":"Shahid A","family":"Junejo","sequence":"first","affiliation":[{"name":"School of Tea and Food Technology Anhui Agricultural University  130 Chang Jiang West Road, Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Tea Plant Biology and Utilization Anhui Agricultural University  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6887-7138","authenticated-orcid":false,"given":"Liping","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Tea and Food Technology Anhui Agricultural University  130 Chang Jiang West Road, Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naifu","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Tea and Food Technology Anhui Agricultural University  130 Chang Jiang West Road, Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibin","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Tea and Food Technology Anhui Agricultural University  130 Chang Jiang West Road, Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuesheng","family":"Xia","sequence":"additional","affiliation":[{"name":"School of Tea and Food Technology Anhui Agricultural University  130 Chang Jiang West Road, Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haisong","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Tea and Food Technology Anhui Agricultural University  130 Chang Jiang West Road, Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcs.2007.09.008"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcs.2012.12.003"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-3010.2009.01747.x"},{"key":"e_1_2_6_5_1","volume-title":"Splanchnic Metabolism and Blood Flow In Man. 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