{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T04:28:01Z","timestamp":1788582481908,"version":"build-2803163510"},"reference-count":63,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,11,12]],"date-time":"2018-11-12T00:00:00Z","timestamp":1541980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Program for Chang Jiang Scholars, Sichuan Province \u2018135\u2019 Breeding Tackle Project","award":["2016NYZ00-2"],"award-info":[{"award-number":["2016NYZ00-2"]}]},{"name":"Sichuan Province Pig Research Innovation \u2018Experts in Feedstuff\u2019 Team"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2019,3,30]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Limited studies have examined links between maternal methyl donor (MET) supplementation and the growth\u2010development characteristics of offspring, and possible underlying mechanisms for such links. This study investigated the effect of maternal or post\u2010weaning MET\u2010supplementation on growth performance, carcass characteristics, and meat quality of the finishing (d 180) offspring. Twenty\u2010four sows were placed on a control (C) or MET\u2010supplemented diet during pregnancy and lactation. Forty\u2010eight female offspring were fed the control or MET\u2010supplemented diet from weaning to 6 months of age, resulting in four study groups (six litters per group): C\/C, C\/MET, MET\/C, and MET\/MET.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Maternal MET\u2010supplementation increased average daily gain (ADG), body weight (BW), lean percentage and longissimus dorsi (LD) of the offspring at day 180 (<jats:italic>P<\/jats:italic> &lt; 0.05), and upregulated the myosin heavy chain IIx, myogenic differentiation and muscle regulatory factor 4 mRNA levels in the LD muscle (<jats:italic>P<\/jats:italic> &lt; 0.05). Meanwhile, offspring from maternal MET\u2010supplementation exhibited a higher pH<jats:sub>24h<\/jats:sub> <jats:italic>post mortem<\/jats:italic> and superoxide dismutase activity, a lower L<jats:sup>*<\/jats:sup><jats:sub>45min<\/jats:sub>, glycolytic potential, malonaldehyde content in the LD muscle, and plasma homocysteine concentration (<jats:italic>P<\/jats:italic> &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Maternal MET\u2010supplementation has a remarkable effect on growth performance, carcass traits, and meat quality of the offspring, which is associated with increased expression levels of myogenic genes and anti\u2010oxidant capacity. \u00a9 2018 Society of Chemical 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