{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T22:59:26Z","timestamp":1775084366240,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2001,5,3]],"date-time":"2001-05-03T00:00:00Z","timestamp":988848000000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2001,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background:<\/jats:title><jats:p>Because of a relative rarity of the cases with an artificial vagina, the incidence of a case with malignant disease arising in the neovagina is extremely rare. A case of adenocarcinoma arising from a neovagina is presented with a review of the literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case:<\/jats:title><jats:p>A neovagina was constructed using the sigmoid colon at the age of 23 for congenital agenesis of the vagina, Rokitansky\u2013K\u00fcster\u2013Hauser syndrome. Subsequently, the patient had regular sexual intercourse for about 20 years. At the age of 53, she came to our outpatient clinic with a complaint of vaginal bleeding, and adenocarcinoma was found at the anterior wall of the neovagina adjoining the introitus. Total resection of the neovagina and adjuvant radiotherapy was performed. The pathological diagnosis was mucinous adenocarcinoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>In view of relatively low incidence of mucinous carcinoma arising in the sigmoid colon along with the ectopic localization, this case may have implications for the understanding of pathogenesis of sigmoid colon cancer. J. Surg. Oncol. 2001; 77:61\u201364. \u00a9 2001 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.1067","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T20:24:15Z","timestamp":1030307055000},"page":"61-64","source":"Crossref","is-referenced-by-count":68,"title":["Mucinous adenocarcinoma arising in a neovagina using the sigmoid colon thirty years after operation: A case report"],"prefix":"10.1002","volume":"77","author":[{"given":"Hisahiko","family":"Hiroi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiharu","family":"Yasugi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Fujii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiaki","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Yoshikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Taketani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,5,3]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"crossref","unstructured":"RugeE:Ersatz der Vagina durch die Flexur mittels Laparotomie. Deut Med Wschr XL 1914.","DOI":"10.1055\/s-0029-1190115"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","unstructured":"RugeE:Flexurplastik bei kongenitaler Aplasie der Scheide. Mschr Geb u Gyn LXXVIII 1928.","DOI":"10.1159\/000305603"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.1991.tb01882.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/S0002-9378(29)90460-9","article-title":"Primary carcinoma of the vagina following a Baldwin reconstruction for congenital absence of the vagina","volume":"18","author":"Ritchie RN","year":"1929","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_1_6_2","first-page":"14","article-title":"Complication tardive apparue au niveau d un vagin artificiel","volume":"19","author":"Lavand Homme P","year":"1938","journal-title":"Brux Med"},{"key":"e_1_2_1_7_2","first-page":"534","article-title":"Primary carcinoma of an artificial vagina. Report of a case","volume":"14","author":"Jakson GW","year":"1959","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_8_2","first-page":"752","article-title":"Congenital absence of the vagina. Long term results of vaginal reconstruction in 175 cases","volume":"100","author":"Cai RW","year":"1968","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/00006250-197207000-00007","article-title":"Squamous cell carcinoma developing in an artificial vagina","volume":"40","author":"Duckler L","year":"1972","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-197304000-00025"},{"key":"e_1_2_1_11_2","first-page":"534","article-title":"Carcinoma arising in the neovagina: Case report and review of the literature","volume":"61","author":"Rotmensch J","year":"1983","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_12_2","first-page":"525","article-title":"Squamous cell carcinoma of the neovagina","volume":"69","author":"Hopkins MP","year":"1987","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(89)90021-8"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1994.1045"},{"key":"e_1_2_1_15_2","volume-title":"Bockus Gastroenterology","author":"William SH","year":"1994"},{"key":"e_1_2_1_16_2","first-page":"681","article-title":"Mucinous colorectal carcinoma: Clinical pathology and prognosis","volume":"54","author":"Okuno M","year":"1988","journal-title":"Am Surg"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197604)37:4<1891::AID-CNCR2820370439>3.0.CO;2-Z"},{"key":"e_1_2_1_18_2","first-page":"3839","article-title":"Risk of anal carcinoma in situ in relation to human papillomavirus type 16 variants","volume":"58","author":"Xi LF","year":"1998","journal-title":"Cancer Res"},{"key":"e_1_2_1_19_2","first-page":"753","article-title":"Variants of squamous cell carcinoma of the anal canal and perianal skin and their relation to human papillomaviruses","volume":"59","author":"Frisch M","year":"1999","journal-title":"Cancer Res"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19970729)72:3<412::AID-IJC7>3.0.CO;2-S"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.1067","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.1067","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T14:32:39Z","timestamp":1700404359000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.1067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,5]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,5]]}},"alternative-id":["10.1002\/jso.1067"],"URL":"https:\/\/doi.org\/10.1002\/jso.1067","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,5]]}}}