{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T12:05:15Z","timestamp":1778328315436,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,2,23]],"date-time":"2004-02-23T00:00:00Z","timestamp":1077494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2004,3,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Total removal of the gastric conduit (TRGC) due to gastric cancer after esophagectomy often results in high operative morbidity and mortality rates, especially when done in the posterior mediastinum. This is one of the reasons for the retro\u2010sternal or subcutaneous route being preferred for gastric conduit replacement in esophageal cancer operation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients<\/jats:title><jats:p>Five out of 680 post\u2010operative esophageal cancer patients underwent TRGC via thoracotomy and laparotomy due to posterior mediastinal gastric conduit cancers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In these patients, advanced gastric cancers were found at an average of 84 months (ranging 57\u2013136 months) after esophageal cancer surgery and preoperative risk factors for TRGC were found in age, nutrition, and pulmonary function. The operative time for TRGC was long (average 670 min) but not associated with operative complications, while blood loss varied among patients, with one with the most operative blood loss dying after surgery due to pyothorax and renal failure. This case, and another early case subjected to TRGC first with thoracotomy then followed by laparotomy, showed more operative blood loss (10,895 and 3,260 ml) than the later three patients (2,370, 1,900, and 1,780 ml), who underwent laparotomy before thoracotomy with ligation of the blood supply of the gastric conduit and lysis of adhesion around gastric conduit in the lower mediastinum from the abdomen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>TRGC in the posterior mediastinum would be safer if operative manipulation were started from laparotomy in order to reduce operative blood loss. J. Surg. Oncol. 2004;85:204\u2013208. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.20017","type":"journal-article","created":{"date-parts":[[2004,2,26]],"date-time":"2004-02-26T20:33:17Z","timestamp":1077827597000},"page":"204-208","source":"Crossref","is-referenced-by-count":16,"title":["Total removal of the posterior mediastinal gastric conduit due to gastric cancer after esophagectomy"],"prefix":"10.1002","volume":"85","author":[{"given":"Hirofumi","family":"Akita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichiro","family":"Doki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ko","family":"Takachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isao","family":"Miyashiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yo","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Ohigashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohei","family":"Murata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"Noura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terumasa","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidetoshi","family":"Eguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingi","family":"Imaoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,2,23]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2050.2000.00116.x"},{"key":"e_1_2_1_3_2","first-page":"336","article-title":"Necessity of screening for multiple primary cancers in patients with esophageal cancer","volume":"8","author":"Noguchi T","year":"2002","journal-title":"Ann Thorac Cardiovasc Surg"},{"key":"e_1_2_1_4_2","first-page":"666","article-title":"Prospective endoscopic follow\u2010up results of reconstructed gastric tube","volume":"50","author":"Motoyama S","year":"2003","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyf083"},{"key":"e_1_2_1_6_2","first-page":"44","article-title":"Secondary early carcinoma in a reconstructed gastric tube after subtotal esophagectomy for early carcinoma of the esophagus","volume":"40","author":"Kitamura K","year":"1993","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_1_7_2","first-page":"371","article-title":"Endoscopic comparison of two cases: Distal resection of reconstructed gastric tube","volume":"49","author":"Yoshida T","year":"2002","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(02)01135-3"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02913915"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.138.3.303"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1999.00981.x"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03218032"},{"key":"e_1_2_1_13_2","first-page":"789","article-title":"Two cases of carcinoma in the gastric tube after esophagectomy for esophageal cancer\u2014the clinical examination of the report in Japan","volume":"99","author":"Nakai M","year":"2002","journal-title":"Nippon Shokakibyo Gakkai Zasshi"},{"key":"e_1_2_1_14_2","first-page":"1275","article-title":"Carcinogenesis of the recontructed gastric tube","volume":"57","author":"Kanda Y","year":"1995","journal-title":"Geka"},{"key":"e_1_2_1_15_2","first-page":"1154","article-title":"A case of carcinoma occurring in the substituted gastric tube after radical resection for an esophageal cancer\u2014a safe and curative reoperative method","volume":"53","author":"Nakamura F","year":"1992","journal-title":"J Jpn Surg Assn"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.5833\/jjgs.29.722"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.5833\/jjgs.32.1991"},{"key":"e_1_2_1_18_2","first-page":"114","article-title":"One case of gastric cancer in the reconstructed gastric tube. 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