{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:03:20Z","timestamp":1760979800943},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,8,23]],"date-time":"2004-08-23T00:00:00Z","timestamp":1093219200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2004,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To define the clinical features and prognosis of patients with abdominal metastasis from primary soft tissue sarcoma (STS) at other sites.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients with abdominal metastasis from STS were identified from the Royal Marsden Hospital Sarcoma Unit prospective database from January 1990 to July 2001.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nineteen patients developed abdominal metastasis out of a cohort of 2127 patients (0.9%) evaluated during the study interval. The median age was 49 (19\u201371) years. The median time to abdominal metastasis from diagnosis of the primary was 27 (8\u201391) months. The presenting complaints were incomplete intestinal obstruction (n\u2009=\u20095), abdominal pain (n\u2009=\u20094), mass (n\u2009=\u20092), gastrointestinal bleed (n\u2009=\u20092), urinary obstruction (n\u2009=\u20092), anorexia (n\u2009=\u20091), and abdominal distension (n\u2009=\u20091). Emergency laparotomy was done for perforative peritonitis (n\u2009=\u20092), intussusception (n\u2009=\u20092), and bleed in spleen (n\u2009=\u20091). Two patients were asymptomatic. The common histologies were myxoid liposarcoma (n\u2009=\u20096) and leiomyosarcoma (n\u2009=\u20094). The median follow\u2010up of survivors post metastasis was 12 months. Abdominal metastatectomy was performed in 16 patients, 3 of these patients had abdominal recurrences. The 1\u2010 and 2\u2010year overall disease specific survival for the 19 patients was 66% (SE\u2009=\u200911%) and 43% (SE\u2009=\u200913%) with a median survival of 13 months (95% CI\u2009=\u200911.8\u201314.7). Metastasectomy was associated with slight improved median post\u2010metastasis survival (33 months vs. 8 months for unresected patients).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Although abdominal metastasis is rare, vigilance is warranted. Symptomatic patients should be examined and investigated thoroughly for metastases. Surgery is the treatment of choice for patients with an acute presentation; however, survival is dismal. J. Surg. Oncol. 2004;87:116\u2013120. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.20105","type":"journal-article","created":{"date-parts":[[2004,8,24]],"date-time":"2004-08-24T07:00:59Z","timestamp":1093330859000},"page":"116-120","source":"Crossref","is-referenced-by-count":16,"title":["Intra\u2010abdominal metastases from soft tissue sarcoma"],"prefix":"10.1002","volume":"87","author":[{"given":"Kasim A.","family":"Behranwala","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pratik","family":"Roy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Giblin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger","family":"A'hern","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cyril","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Meirion","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,8,23]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"1051","article-title":"Malignant fibrous histiocytoma metastatic to the colon presenting as a lower gastrointestinal bleed","volume":"87","author":"Santoro MJ","year":"1992","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197401)33:1<141::AID-CNCR2820330121>3.0.CO;2-N"},{"key":"e_1_2_1_4_2","first-page":"212","article-title":"Malignant fibrous histiocytoma presenting as a bleeding gastric ulcer","volume":"78","author":"Adams HW","year":"1983","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199905000-00002"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19871015)60:8<1800::AID-CNCR2820600822>3.0.CO;2-N"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199301000-00012"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10554"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197806)41:6<2250::AID-CNCR2820410626>3.0.CO;2-W"},{"key":"e_1_2_1_10_2","first-page":"251","article-title":"MFH of the stomach. A report and review of malignant fibrohistiocytic tumours of the alimentary tract","volume":"112","author":"Wright JR","year":"1988","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02587627"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02561588"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19950301)75:5<1120::AID-CNCR2820750511>3.0.CO;2-7"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199602000-00005"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10434-999-0389-5"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.20105","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.20105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T05:31:11Z","timestamp":1700199071000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.20105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,8,23]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,9]]}},"alternative-id":["10.1002\/jso.20105"],"URL":"https:\/\/doi.org\/10.1002\/jso.20105","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,8,23]]}}}