{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:10:46Z","timestamp":1760242246232},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,9,21]],"date-time":"2004-09-21T00:00:00Z","timestamp":1095724800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2004,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Invasive fungal infections have emerged as a significant problem in patients with cancer with the development of better systemic therapies for malignancy and more effective antibacterial agents. The currently available world published medical literature was reviewed on invasive fungal infections in cancer patients with specific attention devoted to the multidisciplinary role of surgery in refractory cutaneous cases. Infections can develop on the forearm where peripheral intravenous catheters had been inserted in cancer patients undergoing cytotoxic chemotherapy. Curative intent begins with systemic contemporary anti\u2010fungal therapy. Following resolution of neutropenia, patients may require radical surgical debridement with negative margins of resection for complete eradication of the fungal infection. Although invasive fungal infections refractory to antifungal systemic therapy in immunocompromised patients undergoing chemotherapy are a rare event, it is critical for surgeons and other multidisciplinary clinicians to recognize these potentially life\u2010threatening infections that may necessitate radical surgical resection for cure. J. Surg. Oncol. 2004;88:21\u201326. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jso.20115","type":"journal-article","created":{"date-parts":[[2004,9,22]],"date-time":"2004-09-22T07:27:36Z","timestamp":1095838056000},"page":"21-26","source":"Crossref","is-referenced-by-count":7,"title":["Invasive cutaneous fungal infections requiring radical resection in cancer patients undergoing chemotherapy"],"prefix":"10.1002","volume":"88","author":[{"given":"Ravi","family":"Radhakrishnan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele L.","family":"Donato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor G.","family":"Prieto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven R.","family":"Mays","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Issam I.","family":"Raad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry M.","family":"Kuerer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,9,21]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-4453(98)90303-6"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/14.Supplement_1.S126"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10610"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198710293171802"},{"key":"e_1_2_1_6_2","first-page":"133","article-title":"Approaches to management of fungal infections in cancer patients","volume":"5","author":"Francis P","year":"1992","journal-title":"Oncology"},{"key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1177\/000313480006600205","article-title":"Diagnosis and treatment of opportunistic infections in immunocompromised surgical patients","volume":"66","author":"Dunn DL","year":"2000","journal-title":"Am Surg"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.10.3.477"},{"key":"e_1_2_1_9_2","first-page":"122","article-title":"Aspergillus: A rare primary organism in soft\u2010tissue infections","volume":"64","author":"Johnson MA","year":"1998","journal-title":"Am Surg"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.123489"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.242.13.1397"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.11.3.409"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1086\/324620"},{"key":"e_1_2_1_14_2","volume-title":"Proceedings of the 42nd Annual Meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy","author":"Maertens J","year":"2002"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200201243460403"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3062.2002.t01-2-02002.x"},{"key":"e_1_2_1_17_2","first-page":"372","volume-title":"Proceedings of the 40th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)","author":"Hachem RY","year":"2000"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.20115","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.20115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T15:21:34Z","timestamp":1700234494000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.20115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,9,21]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,10]]}},"alternative-id":["10.1002\/jso.20115"],"URL":"https:\/\/doi.org\/10.1002\/jso.20115","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,9,21]]}}}