{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:51:10Z","timestamp":1787161870130,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,2,15]],"date-time":"2006-02-15T00:00:00Z","timestamp":1139961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Calcium phosphate cement (CPC) is an injectable biocompatible bone substitute that has been used for various applications in orthopedic surgery. However, no extensive clinical studies of the use of CPC to fill bone cavities after curettage of musculoskeletal tumors have been reported. The present study reviewed the results for 56 musculoskeletal tumors treated by curettage and CPC implantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Assessment was based on clinical examination and radiographic findings. Variables for clinical assessment included pain, limb function, and complications. Median follow\u2010up was 18.5 months (range 6\u201347 months).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>One patient experienced post\u2010operative fractures. Three patients displayed local recurrence. One patient developed post\u2010operative superficial wound infection, and two patients with large bony defect exhibited non\u2010infectious serous discharge. No serious adverse effects such as deep venous thrombosis, pulmonary embolism were encountered. In all cases, CPC was radiographically well adapted to the surrounding host bone as of final follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CPC appears to offer a useful bone substitute for the treatment of musculoskeletal tumors. As the follow\u2010up period for this study was short, further long\u2010term follow\u2010up studies are needed. J. Surg. Oncol. 2006;93: 212\u2013220. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jso.20355","type":"journal-article","created":{"date-parts":[[2006,2,15]],"date-time":"2006-02-15T22:17:10Z","timestamp":1140041830000},"page":"212-220","source":"Crossref","is-referenced-by-count":34,"title":["Calcium phosphate cement in musculoskeletal tumor surgery"],"prefix":"10.1002","volume":"93","author":[{"given":"Akihiko","family":"Matsumine","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuyuki","family":"Kusuzaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takao","family":"Matsubara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Okamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noritaka","family":"Okuyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Miyazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Shintani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsumasa","family":"Uchida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,2,15]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"672","article-title":"A new calcium phosphate setting cement","volume":"62","author":"Brown WE","year":"1983","journal-title":"J Dent Res"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1142\/9789814291064_0126"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.85B2.13255"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200311000-00010"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-002-0458-8"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005131-200006000-00001"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005131-200203000-00001"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.3109\/17453679909000946"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1054\/jhsb.2000.0383"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4636(199824)43:4<428::AID-JBM10>3.0.CO;2-0"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1054\/bjps.1999.3236"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-200212000-00012"},{"key":"e_1_2_1_14_2","first-page":"421","article-title":"Hydroxyapatite cement, a smart biomaterial for craniofacial skeletal tissue engineering","author":"Friedman CD","year":"1998","journal-title":"Surg Technol Int"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000093859.72468.37"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s007760200031"},{"key":"e_1_2_1_17_2","first-page":"287","article-title":"Percutaneous transpedicular vertebroplasty with calcium phosphate cement in the treatment of osteoporotic vertebral compression and burst fractures","volume":"97","author":"Nakano N","year":"2002","journal-title":"J Neurosurg"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-199909000-00001"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7892603"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4636(1999)48:1<36::AID-JBM8>3.0.CO;2-I"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200302000-00007"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200202000-00004"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s007760300032"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200206150-00010"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s007760200100"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.10259"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008505-200211040-00018"},{"key":"e_1_2_1_28_2","unstructured":"BernardsCM ChapmanJ MirzaS:Lethality of embolized Norian bone cement varies with the time between mixing and embolization. 50th Annual Meeting of the Orthopaedic Research Society Paper No: 0254."}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.20355","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.20355","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T08:38:02Z","timestamp":1700037482000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.20355"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2,15]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,3]]}},"alternative-id":["10.1002\/jso.20355"],"URL":"https:\/\/doi.org\/10.1002\/jso.20355","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2,15]]}}}