{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T07:27:51Z","timestamp":1761290871588},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,2,22]],"date-time":"2006-02-22T00:00:00Z","timestamp":1140566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2006,3,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Because renal transplantation recipients require immunosuppressive drugs, they have a higher incidence of subsequent malignancies. Among them, hepatocellular carcinoma (HCC) is common. Although liver resection remains an option for curing HCC, the role of liver resection in renal transplantation recipients remains unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review of liver resection for newly diagnosed HCC in 680 patients was conducted. Among them, 18 patients had undergone prior renal transplantation (RT group). The patient background, tumor characteristics, early and long\u2010term results after liver resection were compared with the other 662 patients who had not previously undergone renal transplantation (non\u2010RT group).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The patient's background characteristics were comparable between RT and non\u2010RT group. The tumor characteristics, postoperative morbidity, and mortality were not significantly different between the two groups. The 5\u2010year disease\u2010free survival rates in RT and non\u2010RT groups were 18.8% and 41.2%, respectively (<jats:italic>P<\/jats:italic>\u2009=\u20090.242), whereas 5\u2010year actuarial survival rates in RT and non\u2010RT groups were 59.1% and 58.3%, respectively (<jats:italic>P<\/jats:italic>\u2009=\u20090.738). Two patients lost their graft kidney 3 and 8 years after liver resection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>With careful protection of the graft kidney, liver resection is still a justified treatment option for HCC in patients who have undergone renal transplantation. J. Surg. Oncol. 2006;93: 273\u2013278. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.20465","type":"journal-article","created":{"date-parts":[[2006,2,22]],"date-time":"2006-02-22T21:49:26Z","timestamp":1140644966000},"page":"273-278","source":"Crossref","is-referenced-by-count":5,"title":["Liver resection for hepatocellular carcinoma in patients who have undergone prior renal transplantation"],"prefix":"10.1002","volume":"93","author":[{"given":"Shao\u2010Bin","family":"Cheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dah\u2010Cherng","family":"Yeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuo\u2010Hsiung","family":"Shu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng\u2010Chung","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei\u2010Chin","family":"Wen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tse\u2010Jia","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang\u2010Ku","family":"P'eng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,2,22]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"907","volume-title":"Adult and pediatric urology","author":"Flechner SU","year":"2001"},{"key":"e_1_2_1_3_2","first-page":"311273","article-title":"Hepatocellular carcinoma after kidney transplantation","volume":"31","author":"Cheng LB","year":"1999","journal-title":"Transplant Proc"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-003-6954-3"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2005.03.010"},{"key":"e_1_2_1_6_2","first-page":"2542","volume-title":"Brenner and Rector's \u201cThe Kidney\u201d","author":"McKay DB","year":"2000"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01655298"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199012203232510"},{"key":"e_1_2_1_9_2","unstructured":"Vital statistics: Department of Health Executive Yuan Taiwan ROC.Health and vital statistics.2003."},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.138.2.185"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.138.11.1198"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(96)80238-8"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4838"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/jso.1160"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1999.01272.x"},{"key":"e_1_2_1_16_2","first-page":"328","article-title":"Long term results after resection of hepatocellular carcinoma: Experience of 480 cases","volume":"40","author":"Kosuge T","year":"1993","journal-title":"Hepatogastroenterol"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1994.01420310070012"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9098(199710)66:2<122::AID-JSO9>3.0.CO;2-F"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200004000-00014"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.133.9.1007"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20391"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800600817"},{"key":"e_1_2_1_23_2","unstructured":"1989 Ed. Maugein Paris C Couinaud Surgical anatomy of the liver revisited"},{"key":"e_1_2_1_24_2","volume-title":"International Union against cancer TNM classification of maligant tumors","author":"Sobin LH","year":"2002"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800830310"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2003.50236"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.20465","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.20465","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T15:31:44Z","timestamp":1700062304000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.20465"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2,22]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,3,15]]}},"alternative-id":["10.1002\/jso.20465"],"URL":"https:\/\/doi.org\/10.1002\/jso.20465","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2,22]]}}}