{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T18:22:16Z","timestamp":1783794136312,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,4,23]],"date-time":"2007-04-23T00:00:00Z","timestamp":1177286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Both ultrasound (US) and computed tomography (CT) can be used to detect supraclavicular lymph node metastases. Aim was to compare US, US <jats:italic>plus<\/jats:italic> fine\u2010needle aspiration (US\u2010FNA), CT, US\u2009+\u2009CT, and US\u2010FNA\u2009+\u2009CT for the detection of these metastases in esophageal or gastric cardia cancer patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between 1994 and 2004, 567 patients underwent US and CT for esophageal or gastric cardia cancer staging. Gold standard was postoperative detection of lymph nodes in the resected specimen, FNA, or a radiological result with follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sensitivities of US (75%), US\u2010FNA (72%), US\u2009+\u2009CT (80%), and US\u2010FNA\u2009+\u2009CT (79%) were higher than sensitivity of CT alone (25%) (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Specificities were high for US\u2010FNA (100%), CT (99%), and US\u2010FNA\u2009+\u2009CT (99%), whereas those of US alone (91%) and US\u2009+\u2009CT (91%) were lower (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). In 4\/65 (6%) patients with true\u2010positive malignant lymph nodes, CT was positive with US and\/or US\u2010FNA being negative. However, in 36\/65 (55%) patients, US and\/or US\u2010FNA were positive with CT being negative.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>US\u2010FNA seems the preferred diagnostic modality for the detection of supraclavicular lymph node metastases in patients with esophageal or gastric cardia cancer. Sensitivity of metastases detection only slightly improves if US\u2010FNA is combined with CT. A prospective, comparative study is however needed. J. Surg. Oncol. 2007;96: 200\u2013206. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.20819","type":"journal-article","created":{"date-parts":[[2007,4,23]],"date-time":"2007-04-23T17:52:19Z","timestamp":1177350739000},"page":"200-206","source":"Crossref","is-referenced-by-count":18,"title":["Ultrasound, computed tomography, or the combination for the detection of supraclavicular lymph nodes in patients with esophageal or gastric cardia cancer: a comparative study"],"prefix":"10.1002","volume":"96","author":[{"given":"Evelyn P.M.","family":"van Vliet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aad van der","family":"Lugt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernst J.","family":"Kuipers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo W.","family":"Tilanus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ate van der","family":"Gaast","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Hermans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter D.","family":"Siersema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,4,23]]},"reference":[{"key":"e_1_2_1_2_2","volume-title":"TNM classification of malignant tumours","author":"Hermanek P","year":"1992"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001574-200407000-00016"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0720-048X(96)01071-6"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1989.01860300043013"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.179.1.2006268"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1053\/crad.2000.0502"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-66-783-203"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01888575"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00413.x"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2281020423"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9098(199603)61:3<214::AID-JSO10>3.0.CO;2-7"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(94)91352-8"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0959-8049(96)00034-2"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199901000-00008"},{"key":"e_1_2_1_16_2","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/S0033-8389(22)02153-4","article-title":"CT of esophageal neoplasms","volume":"27","author":"Halvorsen RA","year":"1989","journal-title":"Radiol Clin North Am"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20724"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.20819","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.20819","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T00:50:14Z","timestamp":1700009414000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.20819"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4,23]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["10.1002\/jso.20819"],"URL":"https:\/\/doi.org\/10.1002\/jso.20819","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,4,23]]}}}