{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T19:23:58Z","timestamp":1773775438264,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2008,1,7]],"date-time":"2008-01-07T00:00:00Z","timestamp":1199664000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2008,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Several studies report the health\u2010related quality of life (HRQoL) after total gastrectomy in short term but long\u2010term results have been less published.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred and seventy two patients underwent total gastrectomy between years 1987\u20131999 for gastric carcinoma. In 2005, 30% of them were still alive. The final study population consisted of 25 patients less than 80 years of age, for whom validated control population data were available. The SF\u201036 and 15D questionnaires were used as QoL instruments. The median follow\u2010up time from surgery was 9.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study group did not differ significantly in any of the SF\u201036 sub scores from the normal population controls. There was no significant difference in the total score in 15D but the patients did statistically significantly worse than the normal population controls in sleeping, elimination and distress. There was significant weight loss during the follow up, but this was not associated with any of HRQoL changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study shows that patients who survived for long\u2010term after total gastrectomy for gastric carcinoma do generally as well as the normal population controls, but depending on the QoL instrument used, may have lower QoL in some sub dimensions. J. Surg. Oncol. 2008;97:121\u2013124. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.20925","type":"journal-article","created":{"date-parts":[[2008,1,7]],"date-time":"2008-01-07T20:46:18Z","timestamp":1199738778000},"page":"121-124","source":"Crossref","is-referenced-by-count":38,"title":["Quality of life in the long\u2010term survivors after total gastrectomy for gastric carcinoma"],"prefix":"10.1002","volume":"97","author":[{"given":"Tuula","family":"Tyrv\u00e4inen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juhani","family":"Sand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harri","family":"Sintonen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isto","family":"Nordback","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,1,7]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0899-9007(99)00123-9"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365526709180059"},{"key":"e_1_2_1_4_2","first-page":"903","article-title":"A randomized clinical trial of pouch reconstruction after total gastrectomy for cancer: Which is the better technique, roux\u2010en\u2010y or interposition?","volume":"48","author":"Nakane Y","year":"2001","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00295908"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(05)80573-2"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199201000-00002"},{"key":"e_1_2_1_8_2","first-page":"367","article-title":"Quality of life in patients with esophagojejunal anastomosis after total gastrectomy for cancer","volume":"14","author":"Scurtu R","year":"2005","journal-title":"Rom J Gastroenterol"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1012719211349"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1998.00747.x"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/003655200750023327"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/110241501750243752"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.3109\/07853890109002086"},{"key":"e_1_2_1_14_2","volume-title":"RAND\u201036 as a measure of health related quality of life. 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