{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:18:14Z","timestamp":1763036294209},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,11,29]],"date-time":"2007-11-29T00:00:00Z","timestamp":1196294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2008,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Factors affecting function, disability and health\u2010related quality of life after allograft\u2010prosthesis composite reconstructions have been poorly studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective study of eighteen patients who underwent reconstruction with proximal femoral allograft\u2010prosthesis composites and answered questionnaires to assess hip function (Postel and Merle d'Aubign\u00e9, self\u2010reported Harris Hip Score), disability (Toronto Extremity Salvage Score), and health\u2010related quality of life (SF\u201036).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median Toronto Extremity Salvage Score was 76 (IQR: 48\u201385), the median self\u2010reported Harris Hip Score was 90 (IQR: 48\u201395) and the median Postel and Merle d'Aubign\u00e9 score was 17 (IQR: 12\u201317). Older age, female gender, and presentation with a pathologic fracture were associated with increased disability and poorest function. The median Physical Component Summary score was 44 (IQR: 39\u201345) and Mental Component Summary scores were 49 (IQR: 46\u201356). Male gender and recurrence of disease were associated with poorer health\u2010related quality of life. There was a high degree of correlation between function, disability scores and Physical Component Summary score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients' characteristics at presentation such as age, gender, and occurrence of a pathologic fracture play an important role in determining disability, function, and health\u2010related quality of life after allograft\u2010prosthesis composite reconstruction of the proximal femur. J. Surg. 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