{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:11:08Z","timestamp":1761743468317},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,3,2]],"date-time":"2011-03-02T00:00:00Z","timestamp":1299024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Follow up for breast cancer patients aims at the timely detection of loco\u2010regional recurrences and contralateral breast cancers (LRR). This study investigates the annual risk of LRR after breast conserving treatment (BCT) and the potential value of mammographic surveillance and\/or routine clinical examination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data on 650 women who underwent BCT were obtained and LRR was divided into parenchymal and non\u2010parenchymal. LRR\u2010free and cumulative LRR\u2010free rates were calculated. In patients where recurrence was diagnosed at a routine clinic visit and had negative mammography (\u201cclinical detection only\u201d group) were also separately examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Median follow up was 115 months, range 9\u2013196. Seventy\u2010three patients had parenchymal and 16 nodal recurrence. The median probability of LRR was 1.4% and of parenchymal LRR was 1.32% per year, remaining constant for up to 168 months. The 16 patients in the \u201cclinical detection only\u201d group relapsed mainly during the first 2 years (annual risk 0.77% and 0.80%, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study shows that the risk of parenchymal LRR remains constant for at least 14 years and is significant enough to warrant routine long\u2010term follow up mammography. Routine clinical examination contributes significantly to the detection of LRR only for the first 2 years. J. Surg. Oncol. 2011; 104:223\u2013227. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.21747","type":"journal-article","created":{"date-parts":[[2011,3,3]],"date-time":"2011-03-03T00:06:17Z","timestamp":1299110777000},"page":"223-227","source":"Crossref","is-referenced-by-count":7,"title":["An evidence based strategy for follow up after breast conserving treatment for breast cancer"],"prefix":"10.1002","volume":"104","author":[{"given":"Michael","family":"Kontos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pratik","family":"Roy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demetrios","family":"Rizos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisham","family":"Hamed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,3,2]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/ctrv.2001.0205"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1987.5.1.62"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.291.6507.1464"},{"key":"e_1_2_5_5_2","first-page":"69","article-title":"The efficacy of breast self\u2010examination","volume":"47","author":"Grady KE:","year":"1992","journal-title":"J Gerontol"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2005.02.006"},{"key":"e_1_2_5_7_2","volume-title":"Early and locally advanced breast cancer\u2014Diagnosis and treatment","author":"National Institute for Health and Clinical Excellence","year":"2009"},{"key":"e_1_2_5_8_2","volume-title":"Improving outcomes in breast cancer\u2014Manual update","author":"National Institute for Health and Clinical Excellence","year":"2002"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.08.8575"},{"key":"e_1_2_5_10_2","volume-title":"The use of imaging in the follow up of patients with breast cancer","author":"The Royal College of Radiologists","year":"1995"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603815"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6604065"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-008-0007-x"},{"key":"e_1_2_5_14_2","unstructured":"NHS Breast Screening Program:http:\/\/www.cancerscreening.nhs.uk\/breastscreen\/publications\/nhsbsp\u2010annualreview2008.pdf accessed January 2010."},{"key":"e_1_2_5_15_2","unstructured":"NHS Breast Screening Program:http:\/\/www.cancerscreening.nhs.uk\/breastscreen\/publications\/nhsbsp\u2010annualreview2009.pdf accessed January 2010."},{"key":"e_1_2_5_16_2","unstructured":"NHS Breast Screening Program:http:\/\/www.ic.nhs.uk\/statistics\u2010and\u2010data\u2010collections\/screening\/breast\u2010cancer\/breast\u2010screening\u2010programme\u2010england\u20102007\u201008 accessed January 2010."},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-007-0586-1"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.21747","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.21747","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.21747","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T04:50:47Z","timestamp":1696913447000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.21747"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,2]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["10.1002\/jso.21747"],"URL":"https:\/\/doi.org\/10.1002\/jso.21747","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,2]]}}}