{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T08:31:45Z","timestamp":1776933105158,"version":"3.51.2"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,6,21]],"date-time":"2011-06-21T00:00:00Z","timestamp":1308614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"crossref","award":["K08CA138764"],"award-info":[{"award-number":["K08CA138764"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Functional outcomes following oncologic total femoral endoprosthetic reconstruction (TFR) are lacking. We compared patient\u2010oriented functional results of TFRs to proximal femur and distal femur reconstructions (PFR and DFR). We also compared function and complications with regard to knee and hip componentry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010four TFR patients were identified from three institutional prospective databases. Forty\u2010one had fixed\u2010 and 13 had rotating\u2010hinge knees, 37 hemiarthroplasty and 17 total hip arthroplasty componentry. Toronto Extremity Salvage Scores (TESS) for n\u2009=\u200927 were compared between groups and to cohorts of PFR (n\u2009=\u200931) and DFR (n\u2009=\u200985) patients using the Mann\u2013Whitney <jats:italic>U<\/jats:italic>\u2010test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Follow\u2010up averaged 4 years. Mechanical complications included five hip dislocations and one femoral malrotation. Four dislocations were in fixed\u2010hinge implants, all in those lacking abductor reattachment. TESS averaged 69.3\u2009\u00b1\u200917.8, statistically decreased from DFR (<jats:italic>P<\/jats:italic>\u2009=\u20090.002) and PFR patients (<jats:italic>P<\/jats:italic>\u2009=\u20090.036). No significant differences were detected between patients in the fixed\u2010hinge (n\u2009=\u200918) and rotating\u2010hinge (n\u2009=\u20099) groups (<jats:italic>P<\/jats:italic>\u2009=\u20090.944), or total hip (n\u2009=\u20098) and hemiarthroplasty (n\u2009=\u200919) groups (<jats:italic>P<\/jats:italic>\u2009=\u20090.633).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>TFR is reserved for extreme cases of limb salvage, portending a poor prognosis overall. Function reflects additive impairments from PFR and DFR. TFR outcomes differ little with rotating\u2010 or fixed\u2010hinge, total hip or hemiarthroplasty implants. J. Surg. Oncol. 2011; 104:561\u2013565. \u00a9 2011 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.22003","type":"journal-article","created":{"date-parts":[[2011,6,21]],"date-time":"2011-06-21T15:40:56Z","timestamp":1308670856000},"page":"561-565","source":"Crossref","is-referenced-by-count":27,"title":["Patient\u2010oriented functional results of total femoral endoprosthetic reconstruction following oncologic resection"],"prefix":"10.1002","volume":"104","author":[{"given":"Kevin B.","family":"Jones","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony M.","family":"Griffin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Coonoor R.","family":"Chandrasekar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Biau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoine","family":"Babinet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Deheshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert S.","family":"Bell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"Grimer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jay S.","family":"Wunder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter C.","family":"Ferguson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,6,21]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"21","article-title":"Total femur and knee joint replacement with a vitallium endoprosthesis","volume":"26","author":"Buchman J","year":"1965","journal-title":"Bull Hosp Joint Dis"},{"key":"e_1_2_7_3_2","first-page":"252","article-title":"Prosthetic replacement using titanium\u2010based alloy artificial total femur incorporating its total hip and total knee joints with plasma\u2010sprayed ceramic coating","volume":"104","author":"Huang GK","year":"1991","journal-title":"Chin Med J (Engl)"},{"key":"e_1_2_7_4_2","first-page":"201","article-title":"Total femur and hip knee joint replacement with plasma\u2010sprayed ceramic coated prosthesis","volume":"10","author":"Huang GK","year":"1990","journal-title":"J Tongji Med Univ"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(03)00041-8"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.3109\/17453678008990883"},{"key":"e_1_2_7_7_2","first-page":"121","article-title":"Total femoral excision and endoprosthetic replacement in osteosarcoma","volume":"99","author":"Katznelson A","year":"1982","journal-title":"Prog Clin Biol Res"},{"key":"e_1_2_7_8_2","first-page":"347","article-title":"Total femoral replacement","volume":"92","author":"Katznelson A","year":"1977","journal-title":"Harefuah"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02484417"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002640000145"},{"key":"e_1_2_7_11_2","first-page":"166","article-title":"Total femur replacement. 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