{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:10:19Z","timestamp":1761844219876},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,9,20]],"date-time":"2012-09-20T00:00:00Z","timestamp":1348099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To evaluate long\u2010term survival in thymic epithelial tumors (TETs), we present our experiences at a single institution in China.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective analysis including 115 patients with TETs from 2001 to 2006. Histological diagnosis was completed based on the new WHO classification system. A univariate and multivariate survival analysis was performed, which included myasthenia gravis (MG), WHO histological type, Masaoka stage, completeness of resection, and adjuvant radiotherapy (RT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>WHO histological subtype was closely correlated with that of Masaoka stage. The overall median survival time was 84.4 months and the 7\u2010year survival rate was 78%. In the univariate analysis, three prognostic factors, including WHO histology type, Masaoka stage and complete resection, were statistically significant. In the analysis of the cases with complete resection, adjuvant RT did not show obvious survival benefit. In the multivariate analysis, Masaoka stage was the only independent factor that predicted long\u2010time survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Thymic carcinoma should be regarded as a different category of the disease due to its aggressive and poorer prognosis. Complete resection of the tumor and Masaoka stage I and II were found to contribute to a better survival. Adjuvant RT is not recommended for patients with complete resection in thymomas. J. Surg. Oncol. 2013;107:167\u2013172. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.23256","type":"journal-article","created":{"date-parts":[[2012,9,20]],"date-time":"2012-09-20T12:49:11Z","timestamp":1348145351000},"page":"167-172","source":"Crossref","is-referenced-by-count":16,"title":["Long\u2010term survival in thymic epithelial tumors: A single\u2010center experience from China"],"prefix":"10.1002","volume":"107","author":[{"given":"Shengping","family":"Shen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinghao","family":"Ai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shun","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,9,20]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3181f1f62d"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19811201)48:11<2485::AID-CNCR2820481123>3.0.CO;2-R"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.1994.tb02936.x"},{"key":"e_1_2_5_5_2","first-page":"145","volume-title":"Pathology and genetics of tumors of the lung, pleura, thymus and heart. Word Health Organization classification of tumors","author":"Muller Hermelink HK","year":"2004"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2010.09.042"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.thorsurg.2010.08.011"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197408)34:2<389::AID-CNCR2820340224>3.0.CO;2-Z"},{"key":"e_1_2_5_9_2","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0022-5223(19)37441-0","article-title":"Results of surgical treatment for thymoma","volume":"87","author":"Shamji F","year":"1984","journal-title":"J Thorac Cardiovasc Surg"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(91)90478-9"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2004.06.090"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.08.074"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10226"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.01.026"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2008.03088.x"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2005.031138"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10665"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200212000-00008"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.10255"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.127.3.755"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23492"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2009.05.038"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3181f20c05"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1569-9293(03)00265-2"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1271010"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1250657"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.08.074"},{"key":"e_1_2_5_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)35673-9"},{"key":"e_1_2_5_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(98)01077-7"},{"key":"e_1_2_5_30_2","first-page":"136","article-title":"Postoperative radiotherapy for a stage I thymoma: A prospective randomized trial in 29 cases","volume":"112","author":"Zhang H","year":"1999","journal-title":"Chin Med J"},{"key":"e_1_2_5_31_2","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e31821f9662"},{"key":"e_1_2_5_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25851"},{"key":"e_1_2_5_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.02.016"},{"key":"e_1_2_5_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24618"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.23256","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.23256","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.23256","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T13:40:54Z","timestamp":1700660454000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.23256"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,20]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["10.1002\/jso.23256"],"URL":"https:\/\/doi.org\/10.1002\/jso.23256","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,20]]}}}