{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:34:42Z","timestamp":1783488882946,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,10,15]],"date-time":"2012-10-15T00:00:00Z","timestamp":1350259200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The surgical treatment of pathological subtrochanteric fractures has been associated with technical difficulties and frequent failures. We analyzed survival, risk factors for death, and outcome after surgical treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study group consisted of 194 patients with pathological subtrochanteric femur fractures operated during 1999\u20132009. Cox multiple\u2010regression analysis was performed to study risk factors and results were expressed as hazard ratios (HR). We included a control group with non\u2010pathological subtrochanteric fractures (n\u2009=\u200987) for comparison.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median age at surgery was 68 (29\u201396) years in the study group and 82 (66\u2013101) in the controls. The 1\u2010year survival rate after surgery was 33% (95% CI: 26\u201340) in the study group and 85% (79\u201393) in the controls. In the study group, the risk of death after surgery was increased for patients \u226565 years of age (HR 1.5, 95% CI: 1.1\u20132.1), with a moderate (HR 2.2, 1.5\u20133.4) and poor (HR 2.9, 1.6\u20135.2) Karnofsky score, with visceral metastases (HR 1.6, 1.1\u20132.3), and perioperative hemoglobin levels &lt;100\u2009g\/L (HR 2.2, 1.3\u20133.7). In patients with pathological fractures, there was no statistically significant difference concerning reoperation rates comparing intramedullary nails (9%) with endoprostheses (6%; <jats:italic>P<\/jats:italic>\u2009=\u20090.3).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Surgery for pathological subtrochanteric femur fractures is a relatively safe and effective procedure. J. Surg. Oncol. 2013;107:498\u2013504. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.23277","type":"journal-article","created":{"date-parts":[[2012,10,15]],"date-time":"2012-10-15T13:15:11Z","timestamp":1350306911000},"page":"498-504","source":"Crossref","is-referenced-by-count":29,"title":["Pathological subtrochanteric fractures in 194 patients: A comparison of outcome after surgical treatment of pathological and non\u2010pathological fractures"],"prefix":"10.1002","volume":"107","author":[{"given":"R\u00fcdiger J.","family":"Weiss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilhelmina","family":"Ekstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bjarne H.","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnny","family":"Keller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minna","family":"Laitinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clement","family":"Trovik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Zaikova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rikard","family":"Wedin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,10,15]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200001000-00006"},{"key":"e_1_2_7_3_2","first-page":"535","article-title":"Impending and actual pathological fractures in patients with bone metastases of the long bones. 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