{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T02:53:26Z","timestamp":1789872806178,"version":"4.0.1"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,11,19]],"date-time":"2013-11-19T00:00:00Z","timestamp":1384819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Among the various controversies in the treatment strategies for patients with thymoma, the optimal mode of resection needs to be defined. To explore whether or not the mode of resection affects the prognosis\/recurrence in patients with thymoma, we evaluated the treatment outcome of patients with resected thymoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred seventy\u2010three nonmyasthenic patients with stage I or II resected thymoma were studied. Patients were divided into two groups: a thymomectomy (resection of thymoma without total thymectomy) group (n\u2009=\u2009100) and a thymothymomectomy (resection of thymoma with total thymectomy) group (n\u2009=\u200973). The differences in the clinicopathological characteristics and prognosis between the two groups were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Myasthenia gravis developed postoperatively in three patients (3%) in the thymomectomy group and in 6 (8%) in the thymothymomectomy group. The 5\u2010 and 10\u2010year overall survival rates in the thymomectomy group were 96.7% and 92.2%, and those in the thymothymomectomy group were 94.0% and 86.2%, respectively (<jats:italic>P<\/jats:italic>\u2009=\u20090.755). Two patients (2%) in the thymomectomy group and 4 (5%) in the thymothymomectomy group experienced recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was no difference in prognosis\/recurrence between the two groups. Thymothymomectomy might not always be necessary for nonmyasthenic patients with stage I or II thymoma. <jats:italic>J. Surg. Oncol. 2014 109:179\u2013183<\/jats:italic>. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.23499","type":"journal-article","created":{"date-parts":[[2013,11,19]],"date-time":"2013-11-19T11:43:56Z","timestamp":1384861436000},"page":"179-183","source":"Crossref","is-referenced-by-count":34,"title":["Does the mode of surgical resection affect the prognosis\/recurrence in patients with thymoma?"],"prefix":"10.1002","volume":"109","author":[{"given":"Kazuo","family":"Nakagawa","sequence":"first","affiliation":[{"name":"Division of Thoracic Surgery National Cancer Center Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisao","family":"Asamura","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery National Cancer Center Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Sakurai","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery National Cancer Center Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun\u2010Ichi","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery National Cancer Center Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Tsuta","sequence":"additional","affiliation":[{"name":"Division of Pathology National Cancer Center Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,11,19]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"National Comprehensive Cancer Network.NCCN Clinical Practice Guidelines in Oncology\u2014Thymomas and thymic carcinomas. 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