{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T22:58:38Z","timestamp":1782255518033,"version":"3.54.5"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,12,11]],"date-time":"2013-12-11T00:00:00Z","timestamp":1386720000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Ampullary (AMP\u2010A) and duodenal adenocarcinomas (DA) are rare tumors. The literature regarding treatment and outcome is very limited. The objective of this project is to compare the outcomes of AMP\u2010A and DA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The records for AMP\u2010A and DA patients between July 1995 and July 2012 at Emory University were reviewed for demographics, pathology, treatment, and survival. Survival rates were estimated by Kaplan\u2013Meier method and compared with log\u2010rank test. A Cox proportional hazard model was fitted to estimate the adjusted effect of AMP\u2010A versus DA on overall survival (OS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ninety\u2010five AMP\u2010A and 66 DA patients were identified. No significant difference between patients with DA and AMP\u2010A was observed for age, gender, or grade. DA presented with larger tumors and higher stages. Treatment included surgery, surgery followed by adjuvant therapy or chemotherapy alone. No OS difference was observed when controlled for stage. AMP\u2010A was sub\u2010classified into intestinal (IAMP), pancreaticobiliary (PBAMP), and unspecified types. IAMP tended to present at a higher grade (<jats:italic>P<\/jats:italic>\u2009=\u20090.045) than PBAMP. No OS difference between the IAMP and PBAMP was observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>After accounting for stage, OS was not significantly different for AMP\u2010A and DA patients. There was no OS difference comparing PBAMP with IAMP. <jats:italic>J. Surg. Oncol. 2014 109:556\u2013560<\/jats:italic>. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.23529","type":"journal-article","created":{"date-parts":[[2013,12,11]],"date-time":"2013-12-11T13:04:59Z","timestamp":1386767099000},"page":"556-560","source":"Crossref","is-referenced-by-count":14,"title":["Treatment utilization and surgical outcome of ampullary and duodenal adenocarcinoma"],"prefix":"10.1002","volume":"109","author":[{"given":"Walid L.","family":"Shaib","sequence":"first","affiliation":[{"name":"Department of Hematology and Oncology Winship Cancer Institute, Emory University Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology Winship Cancer Institute, Emory University Atlanta 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A.","family":"Kooby","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology Winship Cancer Institute, Emory University Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Kauh","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology Winship Cancer Institute, Emory University Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome","family":"Landry","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Winship Cancer Institute, Emory University Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bassel F.","family":"El\u2010Rayes","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology Winship Cancer Institute, Emory University Atlanta 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