{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:54:00Z","timestamp":1789588440198,"version":"build-2803163510"},"reference-count":40,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,3,12]],"date-time":"2014-03-12T00:00:00Z","timestamp":1394582400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Pylorus\u2010preserving pancreatoduodenectomy (PPPD) has been associated with a high incidence of delayed gastric emptying (DGE). There are few studies comparing DGE associated with PPPD and subtotal stomach\u2010preserving pancreatoduodenectomy (SSPPD). Moreover, differences between the procedures with respect to long\u2010term results have not been reported. A prospective randomized study was conducted to compare perioperative complications and long\u2010term nutritional status with PPPD and SSPPD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred patients with periampullary lesions were randomized to receive either PPPD (n\u2009=\u200950) or SSPPD (n\u2009=\u200950). All patients were followed up for 3 years after surgery or to the time of recurrence to evaluate nutritional status for the study. The effects of the procedure, age, and malignancy on changes in nutritional indicators were estimated with linear mixed models. This study was registered at UMIN Clinical Trials Registry (UMIN 000012337).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The incidence of DGE assessed by the International Study Group of Pancreatic Surgery was 20% with PPPD and 12% with SSPPD (<jats:italic>P<\/jats:italic>\u2009=\u20090.414). There were no significant differences between the two procedures on postoperative serum albumin levels, serum total cholesterol levels, and body mass index during the 3\u2010year follow\u2010up period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>SSPPD is equally effective in DGE occurrence rate and long\u2010term nutritional status comparing to PPPD. <jats:italic>J. Surg. Oncol 2014; 109:690\u2013696<\/jats:italic>. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.23566","type":"journal-article","created":{"date-parts":[[2014,3,12]],"date-time":"2014-03-12T09:29:01Z","timestamp":1394616541000},"page":"690-696","source":"Crossref","is-referenced-by-count":69,"title":["A prospective randomized comparison between pylorus\u2010 and subtotal stomach\u2010preserving pancreatoduodenectomy on postoperative delayed gastric emptying occurrence and long\u2010term nutritional status"],"prefix":"10.1002","volume":"109","author":[{"given":"Ippei","family":"Matsumoto","sequence":"first","affiliation":[{"name":"Division of Hepato\u2010Biliary\u2010Pancreatic Surgery, Department of Surgery Kobe University Graduate School of Medicine Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Shinzeki","sequence":"additional","affiliation":[{"name":"Division of Hepato\u2010Biliary\u2010Pancreatic Surgery, 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