{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T02:05:13Z","timestamp":1770343513281,"version":"3.49.0"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,5,26]],"date-time":"2014-05-26T00:00:00Z","timestamp":1401062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the long\u2010term outcomes and risk factors for recurrence after fertility\u2010sparing laparoscopic radical trachelectomy (LRT) in young women with early\u2010stage cervical cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty\u2010eight consecutive patients from four tertiary cancer centers in Korea who had attempted fertility\u2010sparing LRT for early\u2010stage cervical cancer were included in this study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010nine patients completed LRT. The mean age and tumor size were 31 years (range, 20\u201340 years) and 1.8\u2009cm (range, 0.4\u20137\u2009cm), respectively. Twenty\u2010nine patients had a tumor size greater than 2\u2009cm, 22 had deep stromal invasion greater than 50%, and twelve had lymphovascular space invasion. After a median follow\u2010up time of 44 months (range, 3\u2013105 months), nine patients had recurrence and one had died of disease. A tumor size greater than 2\u2009cm (<jats:italic>P<\/jats:italic>\u2009=\u20090.039) and a depth of stromal invasion greater than 50% (<jats:italic>P<\/jats:italic>\u2009=\u20090.016) were significant risk factors for recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This is the largest series on fertility\u2010sparing LRT in young women with early cervical cancer. LRT is a feasible and safe fertility\u2010sparing alternative to radical hysterectomy in these women. A tumor size greater than 2\u2009cm and a depth of stromal invasion greater than 50% were risk factors for recurrence. <jats:italic>J. Surg. Oncol. 2014 110:252\u2013257<\/jats:italic>. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.23631","type":"journal-article","created":{"date-parts":[[2014,5,26]],"date-time":"2014-05-26T06:45:24Z","timestamp":1401086724000},"page":"252-257","source":"Crossref","is-referenced-by-count":67,"title":["Long\u2010term outcomes after fertility\u2010sparing laparoscopic radical trachelectomy in young women with early\u2010stage cervical cancer: An Asan Gynecologic Cancer Group (AGCG) study"],"prefix":"10.1002","volume":"110","author":[{"given":"Jeong\u2010Yeol","family":"Park","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Ulsan College of Medicine Asan Medical Center Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won Deok","family":"Joo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, CHA Gangnam Medical Center CHA University Seoul 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