{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T15:21:31Z","timestamp":1792423291916,"version":"4.5.0"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,7,3]],"date-time":"2014-07-03T00:00:00Z","timestamp":1404345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Asan Institute for Life Science","award":["2014-0306"],"award-info":[{"award-number":["2014-0306"]}]},{"name":"Basic Science Research Program, National Research Foundation (NRF) of Korea, Ministry of Education, Science, and Technology","award":["NRF-2012R1A1A2002039"],"award-info":[{"award-number":["NRF-2012R1A1A2002039"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:sec><jats:label\/><jats:p><jats:bold>Level of Evidence:<\/jats:bold> 2a<\/jats:p><jats:p><jats:bold>Background and Objectives:<\/jats:bold> To investigate the role of <jats:sup>18<\/jats:sup>F\u2010FDG PET\/CT in tumor staging, extent, and volume measurements in oral cavity squamous cell carcinoma (OSCC) patients with\/without dental artifacts on CT or MRI.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> This study was conducted in 63 consecutive patients with OSCC who received initial workups including <jats:sup>18<\/jats:sup>F\u2010FDG PET\/CT and MRI. The results of the imaging modalities were compared to those of pathology, using McNemar's test and the paired <jats:italic>t<\/jats:italic>\u2010test.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Thirty\u2010seven patients (59%) had dental or metallic artifacts obscuring primary tumors. <jats:sup>18<\/jats:sup>F\u2010FDG PET\/CT scanning was superior to MRI in tumor staging (weighted \u03ba\u2009=\u20090.870 vs. 0.518, <jats:italic>P<\/jats:italic>\u2009=\u20090.004) in patients with dental artifacts. In addition, <jats:sup>18<\/jats:sup>F\u2010FDG PET\/CT scans were more specific than MRI in detecting sublingual gland (<jats:italic>P<\/jats:italic>\u2009=\u20090.014) and mouth floor (<jats:italic>P<\/jats:italic>\u2009=\u20090.011) involvement. In patients with dental artifacts, there was a significant discrepancy between primary tumor volume (PTV) measured by pathology and MRI (<jats:italic>P<\/jats:italic>\u2009=\u20090.018), but not between PTV measured from pathology and <jats:sup>18<\/jats:sup>F\u2010FDG PET\/CT at SUV2.5 (<jats:italic>P<\/jats:italic>\u2009=\u20090.245), which showed the highest intraclass correlation coefficient value (0.860).<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> <jats:sup>18<\/jats:sup>F\u2010FDG PET\/CT scans provide accurate tumor staging and volume measurements in OSCC patients with CR\/MRI dental artifacts, leading to improved preoperative planning.<\/jats:p><jats:p><jats:bold>Level of Evidence:<\/jats:bold> 2b<\/jats:p><jats:p>CONDENSED ABSTRACT<\/jats:p><jats:p>This study evaluated the clinical value of <jats:sup>18<\/jats:sup>F\u2010FDG PET\/CT in 63 patients with oral cavity cancers. In 37 (59%) patients with dental artifacts on CT\/MRI, <jats:sup>18<\/jats:sup>F\u2010FDG PET\/CT showed superior results compared to MRI in tumor staging and represented the highest intraclass correlation coefficient value to tumor volume determined by pathology. <jats:italic>J. Surg. Oncol. 2014 110:696\u2013701<\/jats:italic>. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.23691","type":"journal-article","created":{"date-parts":[[2014,7,3]],"date-time":"2014-07-03T11:09:42Z","timestamp":1404385782000},"page":"696-701","source":"Crossref","is-referenced-by-count":28,"title":["Clinical values of <sup>18<\/sup>F\u2010FDG PET\/CT in oral cavity cancer with dental artifacts on CT or MRI"],"prefix":"10.1002","volume":"110","author":[{"given":"Hye Ran","family":"Hong","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soyoung","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Jung","family":"Koo","sequence":"additional","affiliation":[{"name":"Department of Radiology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong\u2010Lyel","family":"Roh","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Seung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung\u2010Ja","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Pathology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung\u2010Ho","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soon Yuhl","family":"Nam","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Yoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Asan Medical Center, University of Ulsan College of Medicine Seoul Republic of Korea"},{"name":"Biomedical Research Institute Korea Institute of Science and Technology Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,7,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2009.07.011"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-0985-4"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2007.03.010"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2006.01.010"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0031766"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2352040134"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semnuclmed.2005.05.001"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.108.051649"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2007.01569.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-88441-7_3"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2011.11.001"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23444"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/001316447303300309"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-008-0918-7"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-009-0586-8"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.254045136"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2011.02.010"}],"container-title":["Journal 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