{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T18:48:39Z","timestamp":1771267719821,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,7,31]],"date-time":"2015-07-31T00:00:00Z","timestamp":1438300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Sentinel lymph nodes (SLN) in popliteal basins are rare, and there is controversy in literature regarding their origin, management, and outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To correlate clinical and pathological features of popliteal basin drainage and analyze the impact of popliteal lymph node drainage on survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Retrospective analysis of SLN biopsies performed at a single institution between 2000 and 2010.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>SLN biopsies were performed in 254 patients with melanoma in lower limbs, 247 of which were evaluated. In this group, there were 59 patients (24%) with a positive SLN. Twenty\u2010seven cases (11%) presented with popliteal drainage, one of which lacked concurrent groin drainage. Among these 27 patients, three (11%) had popliteal metastasis, one of which had exclusive involvement of this basin. Popliteal drainage was associated with worse 5\u2010year disease\u2010free survival (DFS) (<jats:italic>P\u2009<\/jats:italic>=\u20090.028) but not 5\u2010year overall survival (OS) (<jats:italic>P<\/jats:italic>\u2009=\u20090.219) in univariate analysis. In multivariate analysis, Breslow thickness, mitotic index, and positive SLN were prognostic factors for DFS. Only mitotic index correlated significantly with OS (<jats:italic>P\u2009<\/jats:italic>=\u20090.044).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Popliteal drainage seems to be associated with worse prognostic features of the primary tumor. <jats:italic>J. Surg. Oncol. 2015 111:179\u2013182<\/jats:italic>. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.23978","type":"journal-article","created":{"date-parts":[[2015,7,31]],"date-time":"2015-07-31T09:13:22Z","timestamp":1438334002000},"page":"179-182","source":"Crossref","is-referenced-by-count":10,"title":["Popliteal sentinel lymph node involvement in melanoma patients"],"prefix":"10.1002","volume":"112","author":[{"given":"Eduardo","family":"Bertolli","sequence":"first","affiliation":[{"name":"Skin Cancer Department AC Camargo Cancer Center S\u00e3o Paulo\/SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Luiz Barbosa","family":"Bevilacqua","sequence":"additional","affiliation":[{"name":"Breast Cancer Department AC Camargo Cancer Center S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9 Sapata","family":"Molina","sequence":"additional","affiliation":[{"name":"Skin Cancer Department 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