{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T06:36:00Z","timestamp":1780814160312,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,1,11]],"date-time":"2016-01-11T00:00:00Z","timestamp":1452470400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>The aim of this study was to identify predictors of mortality only in patients with malignant pleural effusion (MPE) showing good performance status which required pleural palliative procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients with MPE submitted to pleural palliative procedure were enrolled in a prospective study between 2013 and 2014. Patients with Eastern cooperative oncology group (ECOG) score zero, one, and two were considered with good performance status. The possible prognostic factors were tested for significance using the log\u2010rank test (Kaplan\u2013Meier method) and those with significance on univariate analysis were entered into a multivariable Cox model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 64 patients were included in the analysis. Median follow\u2010up time for surviving patients was 263 days. Median survival for the entire cohort was not reached yet. In the multivariate analysis, gastrointestinal primary site (<jats:italic>P<\/jats:italic>\u2009=\u20090.006), low albumin concentration in the pleural fluid (<jats:italic>P<\/jats:italic>\u2009=\u20090.017), and high serum NLR (<jats:italic>P<\/jats:italic>\u2009=\u20090.007) were associated with mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In our cohort of ECOG 0\u20132 patients with MPE submitted to pleural palliative procedures, gastrointestinal malignancy compared to other sites, low pleural fluid albumin and high NLR were significantly associated with mortality. The identification of these prognostic factors may assist the choice of the optimal palliative technique. <jats:italic>J. Surg. Oncol. 2016;113:570\u2013574<\/jats:italic>. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.24168","type":"journal-article","created":{"date-parts":[[2016,1,11]],"date-time":"2016-01-11T07:36:47Z","timestamp":1452497807000},"page":"570-574","source":"Crossref","is-referenced-by-count":15,"title":["Prognostic factors in patients with malignant pleural effusion: Is it possible to predict mortality in patients with good performance status?"],"prefix":"10.1002","volume":"113","author":[{"given":"Fernando Conrado","family":"Abrao","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery of Hospital S\u00e3o Jos\u00e9 S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata D'Alpino","family":"Peixoto","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology of Hospital S\u00e3o Jos\u00e9 S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor Renato 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