{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T04:21:09Z","timestamp":1780806069659,"version":"3.54.1"},"reference-count":27,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,4,7]],"date-time":"2016-04-07T00:00:00Z","timestamp":1459987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:sec><jats:title>Summary<\/jats:title><jats:p>Isolated vulvar reconstruction using profunda artery\u2010based perforator flaps have good functional as well as quality of life restoration. Surgical techniques, complications, and final evaluation using questionnaires are presented.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Vulvar reconstruction remains a great challenge to reconstructive surgeons. A local fasciocutaneous flap from the medial thigh is a good option with multiple choices of the donor arteries. Here, we extended the clinical application of a profunda perforator artery (PAP) flap with the design of an island pedicle flap.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From 2012 to 2015, 12 female patients with vulvar cancer received tumor ablation and immediate reconstruction using a PAP flap. The flaps (n\u2009=\u200919) were divided into V\u2010Y advancement perforator flap (group I, n\u2009=\u20094) and island pedicle perforator flap (group II, n\u2009=\u200915). All of the demographic data were collected and analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All of the flaps were transferred successfully, and all of the donor sites were closed without morbidities. Group II was superior to group I because of the smaller required flap size (<jats:italic>P<\/jats:italic>\u2009=\u20090.004), the smaller defect size\/flap size ratio (<jats:italic>P<\/jats:italic>\u2009=\u20090.001), and a lower rate of post\u2010op debridement (<jats:italic>P<\/jats:italic>\u2009=\u20090.037). The other parameters were not statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PAP flap is a good choice for vulvar reconstruction. We preferred an island pedicle setting for its thin and pliable fasciocutaneous component and robust flap circulation. The favorable functional and aesthetic results can be achieved with limited donor site morbidities. <jats:italic>J. Surg. Oncol. 2016;113:828\u2013834<\/jats:italic>. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.24233","type":"journal-article","created":{"date-parts":[[2016,4,10]],"date-time":"2016-04-10T17:49:56Z","timestamp":1460310596000},"page":"828-834","source":"Crossref","is-referenced-by-count":27,"title":["Profunda artery perforator flap for isolated vulvar defect reconstruction after oncological resection"],"prefix":"10.1002","volume":"113","author":[{"given":"Tommy Nai\u2010Jen","family":"Chang","sequence":"first","affiliation":[{"name":"Division of Reconstructive Microsurgery Department of Plastic and Reconstructive Surgery Chang Gung Memorial Hospital Linkou Medical Center Taoyuan Taiwan"},{"name":"Chang Gung University College of Medicine Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Che\u2010Hsiung","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Reconstructive Microsurgery Department of Plastic 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