{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T18:28:57Z","timestamp":1784226537805,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,4,22]],"date-time":"2016-04-22T00:00:00Z","timestamp":1461283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The purpose of this study is to assess operative, post\u2010operative, and long\u2010term outcomes in patients who underwent radiation lobectomy (RL) for tumor control and\/or hypertrophy of small future liver remnant (FLR) prior to resection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Right lobar +\/\u2212 segment 4 radioembolization was performed prior to lobectomy\/tri\u2010segmentectomy in patients with hepatic tumor but inadequate FLR. Parenchymal\/tumor volumes were calculated from pre\/post\u2010RL imaging; FLR\/%FLR hypertrophy were determined. Complications were graded by the Clavien\u2010Dindo classification.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirteen patients (HCC n\u2009=\u200910, cholangiocarcinoma n\u2009=\u20092, mCRC n\u2009=\u20091) underwent RL prior to resection. The median time between RL and post\u2010RL imaging was 40 days (23\u2013190 days); the median time to resection was 86 days (30\u2013210 days). Median FLR increased significantly [pre: 33% (22\u201343%); post: 43% (29\u201369%), <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01] to yield a median %FLR hypertrophy of 30% (4\u2013105%). The median hospital stay after resection was 4 days (3\u201311 days). Transient hepatobiliary toxicities normalized post\u2010operatively. Ninety\u2010two percent of resected tumors had &gt;50% pathologic necrosis. Median follow up time after surgery was 604 days (144\u20131,416 days); one death occurred.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this preliminary study, radiation lobectomy was a safe and effective method to achieve remnant liver hypertrophy while providing tumor control. This approach may facilitate safe resection and favorable post\u2010operative outcomes.<jats:italic>J. Surg. Oncol. 2016;114:99\u2013105<\/jats:italic>. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.24269","type":"journal-article","created":{"date-parts":[[2016,4,22]],"date-time":"2016-04-22T15:25:31Z","timestamp":1461338731000},"page":"99-105","source":"Crossref","is-referenced-by-count":99,"title":["<sup>90<\/sup>Y radiation lobectomy: Outcomes following surgical resection in patients with hepatic tumors and small future liver remnant volumes"],"prefix":"10.1002","volume":"114","author":[{"given":"Robert J.","family":"Lewandowski","sequence":"first","affiliation":[{"name":"Department of Radiology Section of Interventional Radiology Northwestern University Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry","family":"Donahue","sequence":"additional","affiliation":[{"name":"Department of Radiology Section of Interventional Radiology Northwestern University Chicago 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