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We performed a comprehensive cost analysis to compare TE\/I\u2009+\u2009ADM and DIEP flap.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A comparative cost analysis of TE\/I\u2009+\u2009ADM and DIEP flap was performed. Medicare reimbursement costs for each procedure and their associated complications were calculated. Pooled probabilities of complications including cellulitis, seroma, skin necrosis, implant removal, flap loss, partial flap loss, and fat necrosis, were calculated using published studies from 2010 to 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Average actual cost for successful TE\/I\u2009+\u2009ADM and DIEP flap were $13\u2009304.55 and $10\u2009237.13, respectively. Incorporating pooled complication data from published literature resulted in an increase in cost to $13\u2009963.46 for TE\/I\u2009+\u2009ADM and $12\u2009624.29 for DIEP flap. The expected costs for successful TE\/I\u2009+\u2009ADM and DIEP flap were $9700.35 and $8644.23, which are lower than the actual costs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>DIEP flap breast reconstruction incurs lower costs compared to TE\/I\u2009+\u2009ADM. These costs are lower at baseline and when additional costs from pooled complications are incorporated.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.24692","type":"journal-article","created":{"date-parts":[[2017,6,7]],"date-time":"2017-06-07T22:16:40Z","timestamp":1496873800000},"page":"439-447","source":"Crossref","is-referenced-by-count":24,"title":["Cost analysis of postmastectomy reconstruction: A comparison of two staged implant reconstruction using tissue expander and acellular dermal matrix with abdominal\u2010based perforator free flaps"],"prefix":"10.1002","volume":"116","author":[{"given":"Bao Ngoc N.","family":"Tran","sequence":"first","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery Department of Surgery Beth Israel Deaconess Medical Center Harvard Medical School Boston Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayotunde","family":"Fadayomi","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery Department of Surgery Beth Israel Deaconess Medical Center Harvard Medical School Boston Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel J.","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery Department of Surgery Beth Israel Deaconess Medical Center Harvard Medical School Boston Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhruv","family":"Singhal","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery Department of Surgery Beth Israel Deaconess Medical Center Harvard Medical School Boston Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5533-3166","authenticated-orcid":false,"given":"Bernard T.","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery Department of Surgery Beth Israel Deaconess Medical Center Harvard Medical School Boston Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,7]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"American Cancer Society. 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