{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T11:57:59Z","timestamp":1783511879324,"version":"3.55.0"},"reference-count":41,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,7,10]],"date-time":"2017-07-10T00:00:00Z","timestamp":1499644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004391","name":"China Medical University Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007300","name":"China Medical University","doi-asserted-by":"publisher","award":["CMU 105\u2010S\u201034"],"award-info":[{"award-number":["CMU 105\u2010S\u201034"]}],"id":[{"id":"10.13039\/501100007300","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>This study evaluated the long\u2010term clinical outcomes among different vascularized lymph node transfers (VLNT) used at our institution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between July 2010 and July 2016, all patients with International Society of Lymphology (ISL) stages II\u2010III who underwent VLNT were evaluated. Demographic and clinical data (limb circumference, infectious episodes, lymphoscintigraphic studies) were recorded pre\u2010operatively. Clinical outcomes, complications, and additional excisional procedures were analyzed post\u2010operatively. At least 2\u2010year follow\u2010up was required for inclusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 83 patients (Stage II:47, Stage III:36) met the inclusion criterion. Mean follow\u2010up was 32.8 months (range, 24\u201049). Lymph node flaps used were groin (<jats:italic>n<\/jats:italic>\u2009=\u200913), supraclavicular (<jats:italic>n<\/jats:italic>\u2009=\u200925), gastroepiploic (<jats:italic>n<\/jats:italic>\u2009=\u200942), ileocecal (<jats:italic>n<\/jats:italic>\u2009=\u20092), and appendicular (<jats:italic>n<\/jats:italic>\u2009=\u20091). Total mean circumference reduction rate was 29.1% (Stage II) and 17.9% (Stage III) (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). A paired <jats:italic>t<\/jats:italic>\u2010test showed that VLNT significantly decreased the number of infections (<jats:italic>P\u2009<\/jats:italic>&lt;\u20090.05). Three patients reported no improvement of the symptoms. Major complications included one flap loss and one donor site hematoma. After the period of follow\u2010up, 18 patients (21.7%) underwent additional excisional procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>VLNT is a promising technique used for the treatment of lymphedema and appears to be more effective in moderate stages (Stage II). Patients with advanced stage lymphedema (Stage III) may benefit from additional excisional procedures.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.24730","type":"journal-article","created":{"date-parts":[[2017,7,11]],"date-time":"2017-07-11T02:12:03Z","timestamp":1499739123000},"page":"671-682","source":"Crossref","is-referenced-by-count":66,"title":["Comparison of long\u2010term clinical outcomes among different vascularized lymph node transfers: 6\u2010year experience of a single center's approach to the treatment of lymphedema"],"prefix":"10.1002","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4646-2676","authenticated-orcid":false,"given":"Pedro","family":"Ciudad","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery China Medical University Hospital Taichung Taiwan"},{"name":"Department of Biological Science and Technology China Medical University Taichung Taiwan"},{"name":"Peru Plastic and Reconstructive Surgery Research 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