{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T16:28:48Z","timestamp":1771000128754,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,9,6]],"date-time":"2017-09-06T00:00:00Z","timestamp":1504656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81572420"],"award-info":[{"award-number":["81572420"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>To determine whether radical resection can benefit patients with advanced gallbladder adenocarcinoma using a Bayesian network (BN) with clinical data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In total, 362 patients who had undergone surgical treatment of gallbladder adenocarcinoma at a tertiary institute were evaluated to establish two BN models using a tree\u2010augmented na\u00efve Bayes algorithm. We then chose 250 patients with T3\u20104N0\u20102M0 stage gallbladder adenocarcinoma to test the posterior probability after the surgical type was taken into account.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 170 patients (\u22647 months) and 137 patients (&gt;7 months) were correctly classified in the median survival time model (accuracy, 84.81%), and 204 patients (\u226412 months), 15 patients (12\u201036 months), 17 patients (36\u201060 months), and 34 patients (&gt;60 months) were correctly classified in the 1\u2010, 3\u2010, and 5\u2010year survival model (accuracy, 74.59%), respectively. Every posterior probability in the two models upregulated the ratio of the longer survival time and suggested a better prognosis for gallbladder adenocarcinoma that can be improved by R0 resection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These BN models indicate that stages T4 and N2 gallbladder adenocarcinoma are not contraindications for surgery and that R0 resection can improve survival in patients with advanced gallbladder adenocarcinoma.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.24797","type":"journal-article","created":{"date-parts":[[2017,9,6]],"date-time":"2017-09-06T14:31:40Z","timestamp":1504708300000},"page":"1123-1131","source":"Crossref","is-referenced-by-count":13,"title":["Decision of surgical approach for advanced gallbladder adenocarcinoma based on a Bayesian network"],"prefix":"10.1002","volume":"116","author":[{"given":"Long\u2010Long","family":"Cong","sequence":"first","affiliation":[{"name":"Department of Hepatobiliary Surgery 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