{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:57:03Z","timestamp":1790791023313,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,8,22]],"date-time":"2017-08-22T00:00:00Z","timestamp":1503360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>This study aims to review our experience in trismus release followed by free flap reconstruction after radiotherapy in oral and oropharyngeal cancer, describe the results obtained in long\u2010term follow\u2010up and identify possible predictors of outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients\u2019 demographics, tumor characteristics and treatment where retrieved. Surgical release and reconstructive procedures were detailed. Interincisor distances (IIDs) where measured preoperatively (PO\u2010IID), intraoperatively after release (IO\u2010IID) and in the last follow\u2010up (FU\u2010IID). Potential predictors of outcome in terms of interincisor long\u2010term gain (LT\u2010gain) and postoperative loss (PO\u2010loss) were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010eight patients were included in our study. The mean LT\u2010gain was 8.9\u2009\u00b1\u20097.0\u2009mm, and the PO\u2010loss was 22.14\u2009\u00b1\u20097.27\u2009mm. Patients with a PO\u2010IID of 10\u2009mm or less had a significant higher LT\u2010gain (<jats:italic>P<\/jats:italic>\u2009=\u20090.038). Predictors of worse outcome included having received a previous maxillectomy during tumor ablation (lower LT\u2010gain, <jats:italic>P<\/jats:italic>\u2009=\u20090.035), and previous buccal mucosa resection (higher PO\u2010loss, <jats:italic>P<\/jats:italic>\u2009=\u20090.044).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Trismus release and free flap reconstruction after radiotherapy in oral and oropharyngeal cancer patients seems to be associated with modest long term results and a high incidence of trismus recurrence, particularly in cases of prior buccal resections or maxillectomy. Patients should be adequately informed and carefully selected before indicating the procedure.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.24806","type":"journal-article","created":{"date-parts":[[2017,8,22]],"date-time":"2017-08-22T19:58:37Z","timestamp":1503431917000},"page":"142-149","source":"Crossref","is-referenced-by-count":13,"title":["Trismus surgical release and free flap reconstruction after radiation therapy in oral and oropharyngeal squamous cell carcinoma"],"prefix":"10.1002","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1747-9356","authenticated-orcid":false,"given":"Alba","family":"de Pablo","sequence":"first","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Branch Plastic and Reconstructive Surgery Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Ting","family":"Chen","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Branch Plastic and Reconstructive Surgery Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyh\u2010Kwei","family":"Chen","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Branch Oral and Maxillofacial Surgery Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung\u2010Kan","family":"Tsao","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital Linkou Branch Plastic and Reconstructive Surgery Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2005.08.001"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-010-0847-4"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10006-010-0220-2"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-007-0345-5"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2015.05.003"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2012.744466"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2014.10.003"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23816"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2010.02.008"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23534"},{"key":"e_1_2_7_12_1","first-page":"323","article-title":"Trismus following treatment of head and neck cancer","volume":"40","author":"Jeremic G","year":"2011","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2015.1037864"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2014.892209"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20760"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2013.03.005"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0092561"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2015.01.016"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2015.05.001"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2015.1133928"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12488"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2015.08.269"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cps.2016.06.002"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200106000-00007"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2009.05.047"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2007.02.015"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2008.12.010"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2013.12.004"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e31827461f8"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000221118.31863.c4"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmrj.2011.08.535"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2004.04.003"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2015.10.011"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2008.00863.x"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2014.892211"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2014.954677"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000122206.03592.CF"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.07.002"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-007-9761-5"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000002950"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.24806","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.24806","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T16:43:39Z","timestamp":1695660219000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.24806"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,22]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1002\/jso.24806"],"URL":"https:\/\/doi.org\/10.1002\/jso.24806","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,22]]}}}