{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T21:25:49Z","timestamp":1790025949747,"version":"4.0.1"},"reference-count":39,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,10,16]],"date-time":"2017-10-16T00:00:00Z","timestamp":1508112000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Despite a large number of studies, the ideal technique of pancreaticojejunostomy (PJ) after pancreaticoduodenectomy (PD) remains debatable. We compared the two most common techniques of PJ (duct\u2010to\u2010mucosa and dunking) in a randomized trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This open\u2010label randomized trial was done at a tertiary care center from January 2009 to October 2015. Patients with resectable periampullary tumours with a pancreatic duct diameter \u22652\u2009mm, requiring PD were randomly assigned to one of the two techniques using computer generated random numbers. The primary outcome was postoperative pancreatic fistula (POPF) rate and secondary outcomes were frequency of other postoperative complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 193 patients were randomized and analyzed (intention\u2010to\u2010treat analysis), 97 in duct\u2010to\u2010mucosa and 96 in dunking group. Both groups were comparable for baseline demographic and clinical profiles. The incidence of POPF in the entire study group was 23.8%. There was no statistically significant difference between the two groups (24.7% vs 22.9%,<jats:italic>P<\/jats:italic>\u2009=\u20090.71). Similarly, the incidence of grades B and C (clinically significant) POPF was comparable (16.5% vs 13.5%,<jats:italic>P<\/jats:italic>\u2009=\u20090.57). Both groups were comparable with respect to the secondary outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The duct\u2010to\u2010mucosa technique of PJ after PD is not superior to the dunking technique with respect to POPF rate. (CTRI\/2010\/091\/000531)<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.24873","type":"journal-article","created":{"date-parts":[[2017,10,16]],"date-time":"2017-10-16T20:06:50Z","timestamp":1508184410000},"page":"389-396","source":"Crossref","is-referenced-by-count":33,"title":["Pancreaticojejunostomy: Does the technique matter? A randomized trial"],"prefix":"10.1002","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7179-8270","authenticated-orcid":false,"given":"Anand N.","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Surgery and Liver Transplantation All India Institute of Medical Sciences New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujoy","family":"Pal","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery and Liver Transplantation All India Institute of Medical Sciences New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivek","family":"Mangla","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery and Liver Transplantation All India Institute of Medical Sciences New Delhi 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