{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T20:57:37Z","timestamp":1789073857519,"version":"build-2803163510"},"reference-count":70,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,8,21]],"date-time":"2018-08-21T00:00:00Z","timestamp":1534809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:p>Lymphedema is a complex disease process with deranged lymphatic transport, fluid accumulation and secondary lipedema and fibrosis. This is a challenging disease to treat with a surgical focus on debulking and physiologic strategies. One strategy is the use of vascularized lymph node transplant (VLNT) to improve physiologic lymph clearance. In this article, VLNT is discussed in detail, including mechanisms, combined strategies, and outcomes.<\/jats:p>","DOI":"10.1002\/jso.25180","type":"journal-article","created":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T15:44:47Z","timestamp":1534952687000},"page":"736-742","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":80,"title":["Lymph node transplantation for the treatment of lymphedema"],"prefix":"10.1002","volume":"118","author":[{"given":"Daniel J","family":"Gould","sequence":"first","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery University of Southern California  California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babak J","family":"Mehrara","sequence":"additional","affiliation":[{"name":"Department of Surgery, Plastic and Reconstructive Surgery, Service Memorial Sloan\u2010Kettering Cancer Center  New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Neligan","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery University of Washington Medical Center  Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4237-2959","authenticated-orcid":false,"given":"Ming\u2010Huei","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Division of Reconstructive Microsurgery Chang Gung Memorial Hospital  Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6883-4816","authenticated-orcid":false,"given":"Ketan M","family":"Patel","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery University of Southern California  California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,21]]},"reference":[{"key":"e_1_2_8_1_2_1","doi-asserted-by":"publisher","DOI":"10.1258\/026835507782655236"},{"key":"e_1_2_8_1_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-88-470-0569-3_29"},{"key":"e_1_2_8_1_4_1","volume-title":"Principles and Practice of Lymphedema Surgery","author":"Cheng M\u2010H","year":"2015"},{"key":"e_1_2_8_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.24170"},{"key":"e_1_2_8_1_6_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-014-3518-8"},{"key":"e_1_2_8_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.20772"},{"key":"e_1_2_8_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cps.2012.08.002"},{"key":"e_1_2_8_1_9_1","first-page":"28","article-title":"Autologous lymph node transfers","volume":"32","author":"Becker C","year":"2016","journal-title":"J Reconstr Microsurg"},{"key":"e_1_2_8_1_10_1","doi-asserted-by":"publisher","DOI":"10.3400\/avd.ra.12.00080"},{"key":"e_1_2_8_1_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181f44658"},{"key":"e_1_2_8_1_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31828bd3b3"},{"key":"e_1_2_8_1_13_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-011-1624-4"},{"key":"e_1_2_8_1_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3182a4d626"},{"key":"e_1_2_8_1_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e318277870f"},{"key":"e_1_2_8_1_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000472452.39097.ed"},{"key":"e_1_2_8_1_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3182268da8"},{"key":"e_1_2_8_1_18_1","first-page":"28","article-title":"Contemporary issues in management of chronic lymphedema: personal reflection on an experience with 1065 patients","volume":"38","author":"Lee BB","year":"2005","journal-title":"Lymphology"},{"key":"e_1_2_8_1_19_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-014-4276-3"},{"key":"e_1_2_8_1_20_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1381957"},{"key":"e_1_2_8_1_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.25034"},{"key":"e_1_2_8_1_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e318272a1b4"},{"key":"e_1_2_8_1_23_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-014-4276-3"},{"key":"e_1_2_8_1_24_1","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1097\/01.prs.0000455358.44986.df","article-title":"From theory to evidence: long\u2010term evaluation of the mechanism of action and flap integration of distal vascularized lymph node transfers","volume":"134","author":"Patel KM","year":"2014","journal-title":"Plast Reconstr Surg"},{"key":"e_1_2_8_1_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000201258.10304.16"},{"key":"e_1_2_8_1_26_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1584570"},{"key":"e_1_2_8_1_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3182426757"},{"key":"e_1_2_8_1_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000437257.78327.5b"},{"key":"e_1_2_8_1_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31819e6529"},{"key":"e_1_2_8_1_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2012.04.017"},{"key":"e_1_2_8_1_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2012.12.010"},{"key":"e_1_2_8_1_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e3181f88e8a"},{"key":"e_1_2_8_1_33_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1986.250.5.H706"},{"key":"e_1_2_8_1_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31819e6529"},{"key":"e_1_2_8_1_35_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1584570"},{"key":"e_1_2_8_1_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01655509"},{"key":"e_1_2_8_1_37_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.276.5317.1423"},{"key":"e_1_2_8_1_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni1013"},{"key":"e_1_2_8_1_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181b03787"},{"key":"e_1_2_8_1_40_1","first-page":"533","article-title":"Combined coumarin and omental transfer treatments for canine proximal obstructive lymphoedema","volume":"72","author":"Knight KR","year":"1991","journal-title":"Int J Exp Pathol"},{"key":"e_1_2_8_1_41_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/353510"},{"key":"e_1_2_8_1_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2010.01213.x"},{"key":"e_1_2_8_1_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-015-1982-2"},{"key":"e_1_2_8_1_44_1","first-page":"156","article-title":"Liposuction reduces arm lymphedema without significantly altering the already impaired lymph transport","volume":"31","author":"Brorson H","year":"1998","journal-title":"Lymphology"},{"key":"e_1_2_8_1_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-015-1736-3"},{"key":"e_1_2_8_1_46_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1544182"},{"key":"e_1_2_8_1_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-015-1736-3"},{"key":"e_1_2_8_1_48_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000763"},{"key":"e_1_2_8_1_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/0007-1226(90)90123-H"},{"key":"e_1_2_8_1_50_1","first-page":"119","article-title":"Transfer of free lymphatic flaps. Microsurgery and anatomical study","volume":"13","author":"Becker C","year":"1987","journal-title":"J Mal Vasc"},{"key":"e_1_2_8_1_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2012.04.017"},{"key":"e_1_2_8_1_52_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e3181f88e8a"},{"key":"e_1_2_8_1_53_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000472453.46721.05"},{"key":"e_1_2_8_1_54_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000001374"},{"key":"e_1_2_8_1_55_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.GOX.0000526267.02633.e7"},{"key":"e_1_2_8_1_56_1","first-page":"244","article-title":"Lymphatic mapping and lymphedema surgery in the breast cancer patient","volume":"4","author":"Patel KM","year":"2015","journal-title":"Gland Surg"},{"key":"e_1_2_8_1_57_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31826d1682"},{"key":"e_1_2_8_1_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-88-470-2766-4_1"},{"key":"e_1_2_8_1_59_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-009-0650-y"},{"key":"e_1_2_8_1_60_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31826d1682"},{"key":"e_1_2_8_1_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2013.06.005"},{"key":"e_1_2_8_1_62_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1351668"},{"key":"e_1_2_8_1_63_1","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1097\/01.prs.0000455357.06868.c0","article-title":"Pre\u2010planning vascularized lymph node transfer with duplex ultrasonography: a prospective evaluation of three common donor sites","volume":"134","author":"Patel KM","year":"2014","journal-title":"Plast Reconstr Surg"},{"key":"e_1_2_8_1_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000000822"},{"key":"e_1_2_8_1_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.22235"},{"key":"e_1_2_8_1_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.30079"},{"key":"e_1_2_8_1_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.30079"},{"key":"e_1_2_8_1_68_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1372482"},{"key":"e_1_2_8_1_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2012.11.026"},{"key":"e_1_2_8_1_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2007.12.022"},{"key":"e_1_2_8_1_71_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000000822"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.25180","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.25180","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jso.25180","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.25180","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T02:12:44Z","timestamp":1694225564000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.25180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,21]]},"references-count":70,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1002\/jso.25180"],"URL":"https:\/\/doi.org\/10.1002\/jso.25180","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,21]]},"assertion":[{"value":"2018-07-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}