{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:59:39Z","timestamp":1790247579132,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,2,18]],"date-time":"2019-02-18T00:00:00Z","timestamp":1550448000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81770566"],"award-info":[{"award-number":["81770566"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\u2009This review aimed to evaluate the safety, feasibility, and effectiveness of synchronous hepatectomy and splenectomy for selected patients with hepatocellular carcinoma and clinically significant portal hypertension compared to hepatectomy alone. A systematic search in electronic databases was conducted. A total of 8 studies including 1445 patients were reviewed. While perioperative safety was satisfactory, synchronous hepatectomy and splenectomy were associated with a significant improvement of 5\u2010year overall survival (odds ratio\u2009=\u20091.81; 95% confidence interval: 1.35, 2.42; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001).<\/jats:p>","DOI":"10.1002\/jso.25392","type":"journal-article","created":{"date-parts":[[2019,2,18]],"date-time":"2019-02-18T12:33:26Z","timestamp":1550493206000},"page":"964-973","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Synchronous hepatectomy and splenectomy vs hepatectomy for selected patients with hepatocellular carcinoma and clinically significant portal hypertension: A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"119","author":[{"given":"Junjie","family":"Kong","sequence":"first","affiliation":[{"name":"Department of Liver Surgery &amp; Liver Transplantation Center West China Hospital of Sichuan University Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery &amp; Liver Transplantation Center West China Hospital of Sichuan University Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5190-3355","authenticated-orcid":false,"given":"Wentao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery &amp; Liver Transplantation Center West China Hospital of Sichuan University Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,18]]},"reference":[{"key":"e_1_2_9_1_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.02.091"},{"key":"e_1_2_9_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27431"},{"key":"e_1_2_9_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2018.03.006"},{"key":"e_1_2_9_1_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/hepr.13047"},{"key":"e_1_2_9_1_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4776"},{"key":"e_1_2_9_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-017-9827-9"},{"key":"e_1_2_9_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(02)00430-0"},{"key":"e_1_2_9_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930350216"},{"key":"e_1_2_9_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.12702"},{"key":"e_1_2_9_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/hepr.12234"},{"key":"e_1_2_9_1_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-005-0524-9"},{"key":"e_1_2_9_1_13_1","first-page":"526","article-title":"Safety of synchronous hepatectomy and splenectomy for patients with hepatocellular carcinoma and hypersplenism","volume":"59","author":"Wang C","year":"2012","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_9_1_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000100"},{"key":"e_1_2_9_1_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-5-13"},{"key":"e_1_2_9_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"},{"key":"e_1_2_9_1_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g7647"},{"key":"e_1_2_9_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2004.01.010"},{"key":"e_1_2_9_1_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-007-9442-3"},{"key":"e_1_2_9_1_20_1","first-page":"957","article-title":"Prognosis of patients with hepatocellular carcinoma and hypersplenism after surgery: a single\u2010center experience from the people's Republic of China","volume":"7","author":"Li C","year":"2014","journal-title":"Oncotargets Ther"},{"key":"e_1_2_9_1_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1386-6346(98)00104-1"},{"key":"e_1_2_9_1_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2012.06241.x"},{"key":"e_1_2_9_1_23_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.17758"},{"key":"e_1_2_9_1_24_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2003.44.6.1053"},{"key":"e_1_2_9_1_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30010-2"},{"key":"e_1_2_9_1_26_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1007122"},{"key":"e_1_2_9_1_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29913"},{"key":"e_1_2_9_1_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2011.12.001"},{"key":"e_1_2_9_1_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510300629"},{"key":"e_1_2_9_1_30_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-011-1975-x"},{"key":"e_1_2_9_1_31_1","doi-asserted-by":"publisher","DOI":"10.1159\/000449336"},{"key":"e_1_2_9_1_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.12199"},{"key":"e_1_2_9_1_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1872-034X.2011.00784.x"},{"key":"e_1_2_9_1_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(99)00294-X"},{"key":"e_1_2_9_1_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2015.05.008"},{"key":"e_1_2_9_1_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(96)70070-7"},{"key":"e_1_2_9_1_37_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i8.2358"},{"key":"e_1_2_9_1_38_1","first-page":"1363","article-title":"Synchronous splenectomy and hepatectomy in patients with hepatocellular carcinoma, hypersplenism and liver cirrhosis","volume":"61","author":"Shi R","year":"2014","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_9_1_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11596-016-1643-2"},{"key":"e_1_2_9_1_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318211caf8"},{"key":"e_1_2_9_1_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2012.08.006"},{"key":"e_1_2_9_1_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2008.05497.x"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.25392","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.25392","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jso.25392","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.25392","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T23:54:49Z","timestamp":1694390089000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.25392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,18]]},"references-count":41,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1002\/jso.25392"],"URL":"https:\/\/doi.org\/10.1002\/jso.25392","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,18]]},"assertion":[{"value":"2018-11-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}