{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T01:45:02Z","timestamp":1769046302527,"version":"3.49.0"},"reference-count":34,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,2,8]],"date-time":"2019-02-08T00:00:00Z","timestamp":1549584000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000133","name":"Agency for Healthcare Research and Quality","doi-asserted-by":"publisher","award":["5T32HS000078"],"award-info":[{"award-number":["5T32HS000078"]}],"id":[{"id":"10.13039\/100000133","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Delayed gastric emptying (DGE) occurs commonly following pancreaticoduodenectomy (PD), but the rate of DGE in the absence of other intra\u2010abdominal complications is poorly understood. The objectives of this study were to define the incidence of DGE and identify risk factors for DGE in patients without pancreatic fistula or other intra\u2010abdominal infections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective cohort study utilizing the American College of Surgeons National Surgical Quality Improvement Program pancreatectomy variables to identify patients with DGE following PD without evidence of fistula or intra\u2010abdominal infection. Multivariable models were developed to assess preoperative, intraoperative, and technical factors associated with DGE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The rate of DGE was 11.7% in 10502 cases without pancreatic fistula or intra\u2010abdominal infection. Patients were more likely to develop DGE if age \u226575 (odds ratio [OR], 1.22; <jats:italic>P<\/jats:italic>\u2009=\u20090.003), male (OR, 1.29; \n<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), underwent pylorus\u2010sparing PD (OR, 1.27; \n<jats:italic>P<\/jats:italic>\u2009=\u20090.004), or had a prolonged operative time (OR, 1.38 if greater than seven vs less than 5\u2009hours; \n<jats:italic>P<\/jats:italic>\u2009=\u20090.005). Factors not associated with DGE included BMI, pathologic indication, and surgical approach.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The incidence of DGE after PD is notable even in patients without other abdominal complications. Identification of patients at increased risk for DGE may aid patient counseling as well as decisions regarding surgical technique, enteral feeding access, and enhanced\u2010recovery pathways.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.25398","type":"journal-article","created":{"date-parts":[[2019,2,9]],"date-time":"2019-02-09T05:39:20Z","timestamp":1549690760000},"page":"925-931","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Risk factors for post\u2010pancreaticoduodenectomy delayed gastric emptying in the absence of pancreatic fistula or intra\u2010abdominal infection"],"prefix":"10.1002","volume":"119","author":[{"given":"Ryan J.","family":"Ellis","sequence":"first","affiliation":[{"name":"Division of Research and Optimal Patient Care American College of Surgeons Chicago Illinois"},{"name":"Department of Surgery Surgical Outcomes and Quality Improvement Center Feinberg School of Medicine Northwestern University Chicago Illinois"},{"name":"Northwestern Institute for Comparative Effectiveness Research in Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aakash R.","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Surgery Surgical Outcomes and Quality Improvement Center Feinberg School of Medicine Northwestern University Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. Brock","family":"Hewitt","sequence":"additional","affiliation":[{"name":"Department of Surgery Surgical Outcomes and Quality Improvement Center Feinberg School of Medicine Northwestern University Chicago Illinois"},{"name":"Department of Surgery Thomas Jefferson University Hospital Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan P.","family":"Merkow","sequence":"additional","affiliation":[{"name":"Division of Research and Optimal Patient Care American College of Surgeons Chicago Illinois"},{"name":"Department of Surgery Surgical Outcomes and Quality Improvement Center Feinberg School of Medicine Northwestern University Chicago Illinois"},{"name":"Northwestern Institute for Comparative Effectiveness Research in Oncology, Robert H. 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