{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T13:08:07Z","timestamp":1785589687975,"version":"3.56.0"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,6,4]],"date-time":"2020-06-04T00:00:00Z","timestamp":1591228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["17411963000"],"award-info":[{"award-number":["17411963000"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of our study was to investigate whether metastatic patterns were associated with the prognosis of patients with FIGO stage IV high\u2010grade serous ovarian cancer (HGSC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively investigated 83 consecutive patients with FIGO stage IV HGSC who underwent primary surgery between April 2005 and June 2013 at our institution. Metastatic patterns were defined as pleural effusion (stage IVA), parenchymal metastases (stage IVB), and extra\u2010abdominal lymph node metastases (stage IVB). Correlations of clinical characteristics and prognosis with metastatic patterns were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010two (50.6%) patients were stage IVA with pleural effusion. Among the remaining stage IVB patients, 19 (22.9%) patients had parenchymal metastases and 22 (26.5%) had extra\u2010abdominal lymph node metastases. FIGO IVA and IVB subclassification did not have a prognostic impact on progression\u2010free survival (PFS) (<jats:italic>P<\/jats:italic>\u2009=\u2009.361). In addition, no differences in PFS were observed among patients presenting the three metastatic patterns (<jats:italic>P<\/jats:italic>\u2009=\u2009.506). The 5\u2010year overall survival (OS) rates of patients with stage IVA and IVB diseases were 35.2% and 34.3%, respectively, (<jats:italic>P<\/jats:italic>\u2009=\u2009.856). In addition, metastatic patterns did not provide additional prognostic information for OS (<jats:italic>P<\/jats:italic>\u2009=\u2009.292).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Neither the subclassification into FIGO IVA and IVB stages nor metastatic patterns of FIGO stage IV provided additional prognostic information.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.25941","type":"journal-article","created":{"date-parts":[[2020,6,5]],"date-time":"2020-06-05T05:38:50Z","timestamp":1591335530000},"page":"315-319","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Metastatic patterns do not provide additional prognostic information for patients with FIGO stage IV high\u2010grade serous ovarian cancer"],"prefix":"10.1002","volume":"122","author":[{"given":"Zheng","family":"Feng","sequence":"first","affiliation":[{"name":"Department of Gynecological Oncology Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Oncology Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Wen","sequence":"additional","affiliation":[{"name":"Department of Gynecological Oncology Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Oncology Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingzhu","family":"Ju","sequence":"additional","affiliation":[{"name":"Department of Gynecological Oncology Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Oncology Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Bi","sequence":"additional","affiliation":[{"name":"Department of Oncology Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Pathology Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gynecological Oncology Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Oncology Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wentao","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Oncology Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Pathology Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2271-2514","authenticated-orcid":false,"given":"Xiaohua","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Gynecological Oncology Fudan University Shanghai Cancer Center  Shanghai China"},{"name":"Department of Oncology Fudan University Shanghai Cancer Center  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21262"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.12614"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(12)60025-3"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2016.06.013"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(06)60033-7"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000000675"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/0284186X.2017.1400691"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2017.05.023"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2017.07.124"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-016-2070-2"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep25408"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1998.5145"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1996.4550"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-0964-9"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2015.97"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2016.05.021"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.09.010"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjso.25941","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.25941","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jso.25941","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.25941","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T04:41:43Z","timestamp":1693716103000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.25941"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,4]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1002\/jso.25941"],"URL":"https:\/\/doi.org\/10.1002\/jso.25941","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,4]]},"assertion":[{"value":"2019-12-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}