{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:59:14Z","timestamp":1792180754121,"version":"4.4.0"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,12]],"date-time":"2020-10-12T00:00:00Z","timestamp":1602460800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The efficacy of pelvic floor peritoneum closure (PC) during endoscopic low anterior resection (E\u2010LAR) of rectal cancer remains unclear. This study aimed to clarify whether pelvic floor PC affected short\u2010term outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study group comprised patients with the pathologically confirmed diagnosis of rectal cancer who underwent E\u2010LAR with pelvic floor PC\u00a0or with no PC\u00a0(NPC) between January 2013 and December 2018 in Southwest Hospital. After propensity score matching (PSM), 584 patients (292 who underwent PC and 292 who underwent NPC) were evaluated. Postoperative indicators, including the rates of complications, anastomotic leakage (AL), reoperation, and inflammation, were observed in the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant difference was observed in the rates of postoperative complications between the PC and NPC groups. The rates of AL were similar (11.3% vs. 9.2%, <jats:italic>p<\/jats:italic>\u2009=\u2009.414). However, the reoperation rate of patients in the PC group was significantly lower than that of patients in the NPC group after AL (36.4% vs. 11.1%, <jats:italic>p<\/jats:italic>\u2009=\u2009.025). The hospital costs were higher in the NPC leakage subgroup (<jats:italic>p<\/jats:italic>\u2009=\u2009.001). Additionally, the serum C\u2010reactive protein\u00a0levels were lower in the PC group on postoperative days (PODs) 1, 3, and 5, whereas procalcitonin\u00a0levels on POD 1 and 3 were lower in the PC group but did not differ significantly on POD 5.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Pelvic peritonization did not affect the rate of complications, especially AL; however, it effectively reduced the reoperation and inflammation rates and reduced hospitalization costs. Other short\u2010term outcomes were similar, which warrant the increased use of pelvic peritonization in endoscopic surgery.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.26238","type":"journal-article","created":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T05:48:46Z","timestamp":1602568126000},"page":"271-277","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Short\u2010term outcomes of pelvic floor peritoneum closure in endoscopic low anterior resection\u00a0of rectal cancer: A propensity score matching analysis"],"prefix":"10.1002","volume":"123","author":[{"given":"Li","family":"Chuan","sequence":"first","affiliation":[{"name":"Department of General Surgery &amp; Rehabilitation, Southwest Hospital Army Medical University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gao","family":"Linfeng","sequence":"additional","affiliation":[{"name":"Department of General Surgery &amp; 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