{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T08:23:39Z","timestamp":1759134219566,"version":"3.40.5"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T00:00:00Z","timestamp":1604016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Describe patient\u2010reported functional outcomes for hand and foot sarcoma survivors treated with limb\u2010sparing surgery and radiation therapy (LSS\u2009+\u2009RT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010four patients with hand\/wrist and foot\/ankle sarcomas treated with LSS\u2009+\u2009RT from 1991 to 2015 were identified. Survivors\u00a0\u226518 years old without subsequent amputation completed self\u2010assessed functional surveys: Toronto upper extremity salvage score (TESS\u2010UE) and Michigan hand outcomes (MHQ) surveys for hand; TESS lower extremity (TESS\u2010LE) and Foot and Ankle Outcomes (FAOS) surveys for foot. Scoring scales: 0\u2013100, MHQ and TESS; \u201026 to 56 and 25\u201059, FAOS core and shoe comfort, respectively. Higher scores denote superior function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Five\u2010year local tumor control was 88%. Fourteen of 24\u00a0hand (58%) and 14\/18 foot (78%) survivors completed surveys. Mean TESS\u2010UE and MHQ scores were 89.4 and 72.8, respectively. Mean TESS\u2010LE, core FAOS, and shoe comfort scores were 92.4, 46.19, and 53.1, respectively. No factors correlated with outcomes. TESS\u2010UE and MHQ scores strongly correlated (<jats:italic>r<\/jats:italic>\u2009=\u2009.87). TESS\u2010LE and FAOS scores were associated with a poor correlation (<jats:italic>r<\/jats:italic>\u2009=\u2009.02 and <jats:italic>r<\/jats:italic>\u2009=\u2009.69).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The largest patient\u2010reported functional outcomes analysis for hand and foot sarcoma survivors treated with LSS\u2009+\u2009RT demonstrates excellent local tumor control and acceptable functional outcomes. Further exploration of optimal functional assessment tools is needed given the potential scope differences.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.26258","type":"journal-article","created":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T20:26:18Z","timestamp":1604089578000},"page":"110-116","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Patient\u2010reported functional outcomes in a cohort of hand and foot sarcoma survivors treated with limb sparing surgery and radiation therapy"],"prefix":"10.1002","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2482-594X","authenticated-orcid":false,"given":"Safia K.","family":"Ahmed","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suneetha","family":"Kaggal","sequence":"additional","affiliation":[{"name":"Department of Biomedical Statistics and Informatics Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William S.","family":"Harmsen","sequence":"additional","affiliation":[{"name":"Department of Biomedical Statistics and Informatics Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica W.","family":"Sawyer","sequence":"additional","affiliation":[{"name":"Essentia Health Cancer Center  Duluth Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0390-1018","authenticated-orcid":false,"given":"Matthew T.","family":"Houdek","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter S.","family":"Rose","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivy A.","family":"Petersen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,30]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198209000-00009"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1998.16.1.197"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)09292-9"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9098(200004)73:4<206::AID-JSO4>3.0.CO;2-5"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/0284186X.2016.1268267"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-006-0001-4"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21301"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.03.084"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/13577140120099173"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6602104"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199504000-00009"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0000000000000107"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.92B3.22331"},{"key":"e_1_2_7_15_1","first-page":"424","article-title":"Case series. 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