{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:26:04Z","timestamp":1771467964326,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,12,17]],"date-time":"2020-12-17T00:00:00Z","timestamp":1608163200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Intraoperative near\u2010infrared imaging (NIFI) of parathyroid glands (PG) by first\u2010generation technology had limited image quality and depth penetration. Second\u2010generation NIFI has recently been introduced. Our aim was to compare (1) capability to detect PG and (2) image quality between older and newer technologies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Accurately detecting PG, as well as, quality of autofluorescence (AF) was compared between an older charge\u2010coupled device (CCD) camera and a newer complementary metal\u2010oxide semiconductor (CMOS). <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>, <jats:italic>t<\/jats:italic> test, and analysis of variance were used for analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 300 patients who underwent parathyroidectomy (PTX) and\/or thyroidectomy (THY) with NIFI, 200 with CCD, and 100 with CMOS. Although both NIFI technologies detected &gt;94% of PG, CMOS was superior to CCD. Comparing AF quality, mean pixel intensity of PG compared with the background was higher with CMOS compared with CCD. When comparing PG detected by NIFI before visual identification by a surgeon, both CCD and CMOS had similar results (25% vs. 22%; <jats:italic>p<\/jats:italic>\u2009=\u2009.3).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both NIFI cameras were excellent at detecting PG. Second\u2010generation NIFI (CMOS) displayed higher detection rates and AF intensity. Although surgeons identified majority of PG before NIFI detection, 25% of PG were identified with NIFI first, suggesting future advancements of this technology may expand its applications during parathyroid\/thyroid operations.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.26336","type":"journal-article","created":{"date-parts":[[2020,12,18]],"date-time":"2020-12-18T14:00:43Z","timestamp":1608300043000},"page":"866-871","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Intraoperative near\u2010infrared imaging of parathyroid glands: A comparison of first\u2010 and second\u2010generation technologies"],"prefix":"10.1002","volume":"123","author":[{"given":"Serkan","family":"Akbulut","sequence":"first","affiliation":[{"name":"Department of Endocrine Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozgun","family":"Erten","sequence":"additional","affiliation":[{"name":"Department of Endocrine Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Gokceimam","sequence":"additional","affiliation":[{"name":"Department of Endocrine Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoo S.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Endocrine Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vikram","family":"Krishnamurthy","sequence":"additional","affiliation":[{"name":"Department of Endocrine Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Heiden","sequence":"additional","affiliation":[{"name":"Department of Endocrine Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judy","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Endocrine Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan","family":"Siperstein","sequence":"additional","affiliation":[{"name":"Department of Endocrine Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1964-9286","authenticated-orcid":false,"given":"Eren","family":"Berber","sequence":"additional","affiliation":[{"name":"Department of Endocrine Cleveland Clinic  Cleveland Ohio USA"},{"name":"Department of General Surgery Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,12,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-006-0397-7"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.3583571"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-016-3571-5"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-017-5424-1"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2015.06.047"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-2503"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2018.11.011"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.26098"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2018.12.044"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2019.4613"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-018-6364-2"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2019.04.072"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1201\/9781420026856"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1109\/JEDS.2014.2306412"},{"key":"e_1_2_7_16_1","unstructured":"Canon Europa N.V. and Canon Europe Ltd. CCD and CMOS sensors\u2014Canon Professional Network;2018."},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2017.06.022"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-018-6963-y"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.21037\/gs.2017.09.04"}],"container-title":["Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.26336","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jso.26336","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jso.26336","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T21:19:12Z","timestamp":1693689552000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jso.26336"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,17]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1002\/jso.26336"],"URL":"https:\/\/doi.org\/10.1002\/jso.26336","archive":["Portico"],"relation":{},"ISSN":["0022-4790","1096-9098"],"issn-type":[{"value":"0022-4790","type":"print"},{"value":"1096-9098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,17]]},"assertion":[{"value":"2020-10-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}