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Nasopharyngeal samples are best at sensitivity detection, especially in early stages of disease and in asymptomatic individuals. Current swab processing involves a 100\u2010 to 1000\u2010fold dilution of the patient sample. Future optimization of testing should focus on using smaller volumes of viral transport media and swab designs to increase comfort and increased viral adhesion.<\/jats:p>","DOI":"10.1002\/jso.26561","type":"journal-article","created":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T04:01:13Z","timestamp":1623038473000},"page":"465-475","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["A review of nasopharyngeal swab and saliva tests for SARS\u2010CoV\u20102 infection: Disease timelines, relative sensitivities, and test optimization"],"prefix":"10.1002","volume":"124","author":[{"given":"Marylin","family":"Roque","sequence":"first","affiliation":[{"name":"Department of Engineering Harvey Mudd College  Claremont California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Proudfoot","sequence":"additional","affiliation":[{"name":"Department of Engineering Harvey Mudd College  Claremont California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vadim","family":"Mathys","sequence":"additional","affiliation":[{"name":"Department of Engineering Harvey Mudd College  Claremont California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Engineering Harvey Mudd College  Claremont California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie","family":"Krieger","sequence":"additional","affiliation":[{"name":"Department of Engineering Harvey Mudd College  Claremont California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Gernon","sequence":"additional","affiliation":[{"name":"Department of Surgery City of Hope Medical Center  Duarte California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kash","family":"Gokli","sequence":"additional","affiliation":[{"name":"Department of Engineering Harvey Mudd College  Claremont California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stanley","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Department of Pathology City of Hope Medical Center  Duarte California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin","family":"Cook","sequence":"additional","affiliation":[{"name":"Department of Surgery City of Hope Medical Center  Duarte California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8934-9959","authenticated-orcid":false,"given":"Yuman","family":"Fong","sequence":"additional","affiliation":[{"name":"Department of Surgery City of Hope Medical Center  Duarte California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,6]]},"reference":[{"unstructured":"AllenJAS AufrichtigA BarnardA et al. 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