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The objectives of this study were to characterize posttreatment surveillance and determine the risk of recurrence following surgical resection of LAMN.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent surgical resection of localized LAMNs in an 11\u2010hospital regional healthcare system from 2000 to 2019 were identified. Posttreatment surveillance regimens were characterized, and rates of disease recurrence were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 114 patients with LAMNs were identified. T\u2010category was pTis for 92 patients (80.7%), pT3 for 7 (6.1%), pT4a for 14 (12.3%), and pT4b for 1 (0.9%). Two patients (1.8%) had a positive resection margin. Posttreatment surveillance was performed for 39 (34.2%) patients and consisted of office visits for 32 (82%) patients, computerized tomography imaging for 30 (77%), magnetic resonance imaging for 5 (13%), colonoscopy for 15 (38%), and serum tumor marker measurement for 12 (31%). After a mean follow\u2010up duration of 4.7 years, no patients experienced tumor recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Posttreatment surveillance is common among patients with LAMNs. However, no patients experienced tumor recurrence, regardless of T\u2010category or margin status, suggesting that routine surveillance following surgical resection of LAMN may be unnecessary.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.26621","type":"journal-article","created":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T14:29:50Z","timestamp":1627828190000},"page":"1115-1120","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Necessity of posttreatment surveillance for low\u2010grade appendiceal mucinous neoplasms"],"prefix":"10.1002","volume":"124","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7794-0864","authenticated-orcid":false,"given":"Aakash R.","family":"Gupta","sequence":"first","affiliation":[{"name":"Surgical Outcomes and Quality Improvement Center (SOQIC), Department of Surgery Northwestern Medicine Chicago Illinois 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