{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:48:45Z","timestamp":1786978125383,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T00:00:00Z","timestamp":1635897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>There are reports of outcomes of elective major cancer surgery during the COVID\u201019 pandemic. We evaluated if reinforcement of hand hygiene, universal masking, and distancing as a part of pandemic precautions led to a decrease in the incidence of surgical site infections (SSIs) in major oncologic resections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Propensity score matching using the nearest neighbor algorithm was performed on 3123 patients over seven covariates (age, comorbidities, surgery duration, prior treatment, disease stage, reconstruction, and surgical wound type) yielding 2614 matched (pre\u2010COVID 1612\u00a0and COVID 1002) patients. Conditional logistic regression was used to identify if SSI incidence was lower amongst patients operated during the pandemic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was a 4.2% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006) decrease in SSI in patients operated during the pandemic. On multivariate regression, surgery during the COVID\u201019 period (odds ratio [OR]\u2009=\u20090.77; 95% confidence interval [CI]\u2009=\u20090.61\u20130.98;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03), prior chemoradiation (OR\u2009=\u20092.46; CI\u2009=\u20091.45\u20134.17;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), duration of surgery &gt;4\u2009h (OR\u2009=\u20092.17; 95%CI\u2009=\u20091.55\u20133.05;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and clean contaminated wounds (OR\u2009=\u20092.50; 95% CI\u2009=\u20091.09\u20132.18;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012) were significantly associated with SSI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Increased compliance with hand hygiene, near\u2010universal mask usage, and social distancing during the COVID\u201019 pandemic possibly led to a 23% decreased odds of SSI in major oncologic resections. Extending these low\u2010cost interventions in the post\u2010pandemic era can decrease morbidity associated with SSI in cancer surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jso.26738","type":"journal-article","created":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T04:11:22Z","timestamp":1635912682000},"page":"327-335","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Surgical Site Infections in patients undergoing major oncological surgery during the COVID\u201019 paNdemic (SCION): A propensity\u2010matched analysis"],"prefix":"10.1002","volume":"125","author":[{"given":"Gouri","family":"Pantvaidya","sequence":"first","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3813-4680","authenticated-orcid":false,"given":"Shalaka","family":"Joshi","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8385-2836","authenticated-orcid":false,"given":"Prakash","family":"Nayak","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadhana","family":"Kannan","sequence":"additional","affiliation":[{"name":"Clinical Research Secreteriat Advanced Centre for Treatment, Research and Education in Cancer  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwin","family":"DeSouza","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pabashi","family":"Poddar","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1722-4337","authenticated-orcid":false,"given":"Gagan","family":"Prakash","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preeti","family":"Vijaykumaran","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepa","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richa","family":"Vaish","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8489-6825","authenticated-orcid":false,"given":"Shraddha","family":"Patkar","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9767-3046","authenticated-orcid":false,"given":"Devayani","family":"Niyogi","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poonam","family":"Joshi","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikram","family":"Chaudhari","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikas","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saumya","family":"Mathews","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. S.","family":"Pramesh","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajendra A.","family":"Badwe","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4323-753X","authenticated-orcid":false,"given":"Ajay","family":"Puri","sequence":"additional","affiliation":[{"name":"Department of Surgery Tata Memorial Hospital and Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31821175f8"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijmr.IJMR_2131_20"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2011595"},{"key":"e_1_2_8_5_1","unstructured":"Surgical Site Infection (SSI) Event. 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