{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T16:20:48Z","timestamp":1779294048339,"version":"3.51.4"},"reference-count":47,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T00:00:00Z","timestamp":1642464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Lung cancer patients slated for surgery are at high risk of venous thromboembolism (VTE). Precise risk assessment is necessary for providing proper thromboprophylaxis and reducing morbidity and mortality of VTE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A multicenter, observational, cross\u2010sectional cohort study, involving patients with primary lung cancer undergoing surgery, was carried out from August 2016 to December 2019. All patients were assessed according to the Caprini risk assessment model (RAM) and a modified scoring system incorporating elevated <jats:sc>D<\/jats:sc>\u2010dimer and new stratification of surgical time. The endpoint was confirmed VTE or patient discharge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 1205 patients, 87 (7.2%) were diagnosed with VTE. The area under the curve of modified scores for VTE was 0.759, which was larger than that of the original one (0.589) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). By modified Caprini scoring system, a higher score was associated with increased VTE risk (odds ratio [OR], 1.345; 95% confidence interval [CI], 1.197\u20131.512; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and there was an increased OR of 4.090 (95% CI, 2.472\u20136.768, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) for VTE in high\u2010risk category patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Modified Caprini RAM showed an improved prediction of high\u2010risk patients with an elevated likelihood of postoperative VTE compared to the original one.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.26794","type":"journal-article","created":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T19:32:49Z","timestamp":1642534369000},"page":"933-942","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Validation of a modified Caprini risk assessment model in lung cancer patients undergoing surgery: Results of a multicenter cross\u2010sectional observational study"],"prefix":"10.1002","volume":"125","author":[{"given":"Lihui","family":"Ke","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Beijing Institute of Respiratory Medicine and Beijing Chao\u2010Yang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Songping","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Beijing Institute of Respiratory Medicine and Beijing Chao\u2010Yang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, West China Hospital, West China School of Nursing Sichuan University  Chengdu Sichuan 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