{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T05:09:32Z","timestamp":1785042572411,"version":"3.55.0"},"reference-count":66,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T00:00:00Z","timestamp":1663286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Colorectal cancer (CRC) sidedness is recognized as a prognostic factor for survival; left\u2010sided colorectal cancer\u00a0is associated with better outcomes than right\u2010sided colon cancer (RsCC). We aimed to evaluate the influence of obesity on CRC sidedness and determine how race, age, and sex affect mortality among overweight and obese individuals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A survey\u2010weighted analysis was conducted using data obtained from the National Inpatient Sample\u00a0between 2016 and 2019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 24\u2009549 patients with a diagnosis of CRC and a reported body mass index (BMI), 13.6% were overweight and 49.9% were obese. The race distribution was predominantly non\u2010Hispanic Whites (69.7%), followed by Black (15.6%), Hispanic (8.7%), and other race (6.1%). Overweight (BMI: 25\u221229.9) and obese (BMI:\u00a0\u226530) individuals were more likely to have RsCC (adjusted OR [aOR]\u2009=\u20091.28; 95% CI: 1.17\u22121.39, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001 and aOR\u2009=\u20091.45; 95% CI: 1.37\u22121.54, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, respectively). Obese Black individuals were more likely to have RsCC as compared to their White counterparts (aOR\u2009=\u20091.23; 95% CI: 1.09\u22121.38).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Obesity is associated with an increased risk of RsCC. In addition, racial disparities in CRC sidedness and outcomes are most pronounced among obese patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.27096","type":"journal-article","created":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T15:34:23Z","timestamp":1663342463000},"page":"109-118","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Race, age, and sex differences on the influence of obesity on colorectal cancer sidedness and mortality: A national cross\u2010sectional study"],"prefix":"10.1002","volume":"127","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5966-3966","authenticated-orcid":false,"given":"Mark B.","family":"Ulanja","sequence":"first","affiliation":[{"name":"Christus Ochsner St. Patrick Hospital Lake Charles Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carnot","family":"Ntafam","sequence":"additional","affiliation":[{"name":"Department of Radiology Children's Hospital Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5071-1826","authenticated-orcid":false,"given":"Bryce D.","family":"Beutler","sequence":"additional","affiliation":[{"name":"Department of Radiology, Keck School of Medicine University of Southern California Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Antwi\u2010Amoabeng","sequence":"additional","affiliation":[{"name":"Christus Ochsner St. Patrick Hospital Lake Charles Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganiyu A.","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medical Sciences University of Cape Coast  Cape Coast Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reginald N.","family":"Ulanja","sequence":"additional","affiliation":[{"name":"Department of 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