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Current study explores the disparities in survival for patients with MBD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with the diagnosis of MBD at presentation for the five most common primary anatomical sites were extracted from Surveillance, Epidemiology, and End Results Census tract\u2013level dataset (2010\u20132016). Kaplan\u2013Meier and Cox Proportional Hazard models were used to evaluate survival, and prognostic factors for each cohort. Prognostic significance of socioeconomic status (SES) and insurance status were ascertained.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The five most common anatomical\u2010sites with MBD at presentation included \u201clung\u201d (<jats:italic>n<\/jats:italic>\u2009=\u200959\u2009739), \u201cprostate\u201d (<jats:italic>n<\/jats:italic>\u2009=\u200919\u2009732), \u201cbreast\u201d (<jats:italic>n<\/jats:italic>\u2009=\u200916\u2009244), \u201crenal and urothelium\u201d (<jats:italic>n<\/jats:italic>\u2009=\u20097718) and \u201ccolon\u201d (<jats:italic>n<\/jats:italic>=\u20093068). Lower SES was an independent risk factor for worse disease\u2010specific survival (DSS) for patients with MBD originating from lung, prostate, breast and colon. Lack of insurance was an independent risk factor for worse DSS for MBD patients with primary tumors in lung and breast.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>MBD patients from the five most common primary sites demonstrated SES and insurance\u2010related disparities in disease\u2010specific survival. This is the first and largest study to explore SES and insurance\u2010related disparities among patients specifically afflicted with MBD. Our findings highlight vulnerability of patients with MBD across multiple primary sites to financial toxicity.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.27097","type":"journal-article","created":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T14:38:24Z","timestamp":1663598304000},"page":"159-173","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Socioeconomic and insurance\u2010related disparities in disease\u2010specific survival among patients with metastatic bone disease"],"prefix":"10.1002","volume":"127","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0667-5063","authenticated-orcid":false,"given":"Muhammad Umar","family":"Jawad","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery Samaritan Health System Corvallis Oregon USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad H.","family":"Pollock","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences UC Davis School of Medicine Sacramento California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barton L.","family":"Wise","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine UC Davis School of Medicine Sacramento California USA"},{"name":"Department of Orthopaedic Surgery UC Davis School of Medicine Sacramento California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren N.","family":"Zeitlinger","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery UC Davis School of Medicine Sacramento California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edmond F.","family":"O' Donnell","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery UC Davis School of Medicine Sacramento California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janai R.","family":"Carr\u2010Ascher","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine UC Davis School of Medicine Sacramento California USA"},{"name":"Department of Orthopaedic Surgery UC Davis School of Medicine Sacramento California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4777-2617","authenticated-orcid":false,"given":"Amy","family":"Cizik","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery University of Utah Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Betty","family":"Ferrell","sequence":"additional","affiliation":[{"name":"Department of Nursing and Palliative Care City of Hope Duarte California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven W.","family":"Thorpe","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery UC Davis School of Medicine Sacramento California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3660-774X","authenticated-orcid":false,"given":"R. 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