{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:27:55Z","timestamp":1740104875423,"version":"3.37.3"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T00:00:00Z","timestamp":1672185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Several techniques have been proposed for the closure of loop ileostomy. This is the first study comparing bowel function and outcomes of two different hand\u2010sewn surgical techniques used for the closure of diverting protective loop ileostomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>In this prospective, randomized, double\u2010blind clinical trial, 40 patients with a history of rectal cancer, low anterior resection, and diverting loop ileostomy who were candidates for ileostomy reversal were included and randomly assigned into two groups, hand\u2010sewn direct repair of the ileal defect (group A) and resection and hand\u2010sewn anastomosis of the ileum (group B).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of patients was 56.42 and 52.10 years in groups A and B, respectively. Regarding early postoperative period, group A developed earlier first gas passage (1.68 vs. 2.25 days, <jats:italic>p<\/jats:italic>\u2009=\u20090.041) and stool passage (2.10 vs. 2.80 days, <jats:italic>p<\/jats:italic>\u2009=\u20090.032). Group A also revealed shorter operating time (83.68 vs. 89.50\u2009min, <jats:italic>p<\/jats:italic>\u2009=\u20090.040) and hospital stay (4.73 vs. 6.80 days, <jats:italic>p<\/jats:italic>\u2009=\u20090.001). None of the participants in both groups developed signs of bowel obstruction during the early and late postoperative follow\u2010up period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Direct hand\u2010sewn repair for the closure of diverting loop ileostomy is a safe technique with better postoperative bowel function, oral diet tolerance, and less hospital stay compared to resection and hand\u2010sewn anastomosis of the ileum.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.27185","type":"journal-article","created":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T15:56:30Z","timestamp":1672242990000},"page":"798-805","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Hand\u2010sewn direct repair versus resection and hand\u2010sewn anastomosis techniques for the reversal of diverting loop ileostomy after lower anterior rectal resection surgery: A randomized clinical trial"],"prefix":"10.1002","volume":"127","author":[{"given":"Mohammad Reza","family":"Keramati","sequence":"first","affiliation":[{"name":"Department of Surgery Tehran University of Medical Sciences Tehran Iran"},{"name":"Colorectal Research Center Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Mostafa","family":"Meshkati Yazd","sequence":"additional","affiliation":[{"name":"Department of Surgery Tehran University of Medical Sciences Tehran Iran"},{"name":"Colorectal Research Center Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5454-495X","authenticated-orcid":false,"given":"Reza","family":"Shahriarirad","sequence":"additional","affiliation":[{"name":"Thoracic and Vascular Surgery Research Center Shiraz University of Medical Sciences Shiraz Iran"},{"name":"School of Medicine Shiraz University of Medical Sciences Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Mohsen","family":"Ahmadi Tafti","sequence":"additional","affiliation":[{"name":"Department of Surgery Tehran University of Medical Sciences Tehran Iran"},{"name":"Colorectal Research Center Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alireza","family":"Kazemeini","sequence":"additional","affiliation":[{"name":"Department of Surgery Tehran University of Medical Sciences Tehran Iran"},{"name":"Colorectal Research Center Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Behnam","family":"Behboudi","sequence":"additional","affiliation":[{"name":"Department of Surgery Tehran University of Medical Sciences Tehran Iran"},{"name":"Colorectal Research Center Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Sadegh","family":"Fazeli","sequence":"additional","affiliation":[{"name":"Department of Surgery Tehran University of Medical Sciences Tehran Iran"},{"name":"Colorectal Research Center Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Keshvari","sequence":"additional","affiliation":[{"name":"Department of Surgery Tehran University of Medical Sciences Tehran Iran"},{"name":"Colorectal Research Center Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,28]]},"reference":[{"issue":"86","key":"e_1_2_10_2_1","first-page":"1562","article-title":"Defunctioning loop ileostomy with low anterior resection for distal rectal cancer: should we make an ileostomy as a routine procedure? 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