{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T15:50:37Z","timestamp":1769183437157,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T00:00:00Z","timestamp":1677715200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background ond Objectives<\/jats:title><jats:p>Complete cytoreductive surgery (CRS) may prolong survival for selected patients with peritoneal carcinomatosis from colorectal cancer (CRC). However, there is a paucity of data on outcomes following incomplete procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with incomplete CRS for well\u2010differentiated (WD) and moderate\/poorly\u2010differentiated (M\/PD) appendiceal cancer, right and left CRC were identified at a single tertiary center (2008\u20132021).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 109 patients, 10% were WD and 51% M\/PD appendiceal cancers, and 16% right and 23% left CRC. There were no differences in gender, BMI (mean\u2009=\u200927), ASA score, previous abdominal surgery (72%), and extent of CRS. The PC Index differed between appendiceal and colorectal cancers (mean\u2009=\u200927 vs. 17, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). Overall, the perioperative outcomes were similar among the groups, with 15% experiencing complications. Postoperatively, 61% received chemotherapy, and 51% required \u22651 subsequent procedure. The 1 and 3\u2010year survival for the WD, M\/PD, right and left CRC subgroups were 100%, 67%, 44%, 51%, and 88%, 17%, 12%, and 23%, respectively (<jats:italic>p<\/jats:italic>\u2009=\u20090.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Incomplete CRS was associated with significant morbidity and number of subsequent palliative procedures. Prognosis correlated with histologic subtype; WD appendiceal cancer patients having superior outcomes, while those with right sided CRC the worst survival. These data may help guiding expectations in the setting of incomplete procedures.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.27223","type":"journal-article","created":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T14:57:30Z","timestamp":1677769050000},"page":"1028-1034","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Incomplete cytoreductive surgery for appendiceal and colorectal peritoneal carcinomatosis: Characteristics and outcomes of an overlooked group"],"prefix":"10.1002","volume":"127","author":[{"given":"Paolo","family":"Goffredo","sequence":"first","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center New York New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Aguirre","sequence":"additional","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center New York New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mostafa","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center New York New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Kleiman","sequence":"additional","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center New York New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5054-8192","authenticated-orcid":false,"given":"Andrea","family":"Cercek","sequence":"additional","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center New York New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Joshua Smith","sequence":"additional","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center New York New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7045-2112","authenticated-orcid":false,"given":"Philip B.","family":"Paty","sequence":"additional","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center New York New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Weiser","sequence":"additional","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center New York New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio","family":"Garcia\u2010Aguilar","sequence":"additional","affiliation":[{"name":"Department of Surgery Memorial Sloan Kettering Cancer Center New York New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9833-2625","authenticated-orcid":false,"given":"Garrett 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