{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T00:29:06Z","timestamp":1717720146846},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T00:00:00Z","timestamp":1709078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objective<\/jats:title><jats:p>The aim of this study was to evaluate the prevalence and risk factors associated with perioperative venous thromboembolism (VTE) in patients undergoing major oncologic surgery using an epidural catheter (EC) for postoperative analgesia with mechanical prophylaxis and without chemoprophylaxis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Six hundred and twenty\u2010six\u00a0patients undergoing major oncologic surgery from 2009 to 2023 were evaluated. VTE was defined as deep vein thrombosis above the level of the knee. Lower extremity venous duplexes (LEVDs) were done preoperatively and postoperatively after the EC was removed. All patients received mechanical thromboprophylaxis, but not chemical prophylaxis, while the EC was in place. A generalized linear multivariable model was constructed to identify risk factors that predict pre and postoperative VTE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>29\/626 patients (4.6%) were found to have preoperative VTE. 16\/626 (2.6%) were found to have a postoperative VTE when their preoperative LEVD was negative. In comparison to patients without preoperative VTE, those with VTE were more likely to be male, anticoagulated, and have a history of coronary artery disease.\u00a0Patients in the postoperative VTE group were older, male, anticoagulated, and had a history of VTE. On multivariable analysis, previous history of VTE was the risk factor most strongly associated with both pre and postoperative VTE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Oncologic patients undergoing elective abdominopelvic surgery with epidural analgesia should be screened in the perioperative setting with LEVD to identify VTE and possibly prevent PE.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.27609","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T05:22:58Z","timestamp":1709184178000},"page":"1089-1096","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Seek and ye shall find: The utility of perioperative VTE screening in high\u2010risk oncologic patients undergoing abdominopelvic surgery"],"prefix":"10.1002","volume":"129","author":[{"given":"Eric R.","family":"Pletcher","sequence":"first","affiliation":[{"name":"Division of Surgical Oncology Cedars\u2010Sinai Medical Center Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allison","family":"Nguyen\u2010Thai","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology Cedars\u2010Sinai Medical Center Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiffany","family":"Lim","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology Cedars\u2010Sinai Medical Center Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan W.","family":"Silberman","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology Cedars\u2010Sinai Medical Center Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,2,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020007338"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.27772"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-020-02180-x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000005697"},{"key":"e_1_2_9_6_1","unstructured":"National Comprehensive Cancer Network. Cancer\u2010Associated Venous Thromboembolic Disease. (Version 2.2023).\u00a0https:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/vte.pdf"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.3118"},{"key":"e_1_2_9_8_1","unstructured":"GordonM LumleyT. 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