{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T17:17:30Z","timestamp":1779124650474,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T00:00:00Z","timestamp":1713657600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000048","name":"American Cancer Society","doi-asserted-by":"publisher","award":["RSG\u201022\u2010106\u201001\u2010CSCT"],"award-info":[{"award-number":["RSG\u201022\u2010106\u201001\u2010CSCT"]}],"id":[{"id":"10.13039\/100000048","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000982","name":"Conquer Cancer Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000982","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014285","name":"Society of University Surgeons","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014285","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Oncology"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Given persistent racial disparities in breast cancer outcomes, this study explores racial differences in disease\u2010specific mortality and surgical management among patients with microinvasive ductal carcinoma in situ (DCIS\u2010MI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Surveillance, Epidemiology, and End Results Program was queried for patients aged 18+ years with DCIS\u2010MI between January 1, 2010 and December 31, 2018. The study cohort was divided into non\u2010Hispanic Black (NHB) and non\u2010Hispanic White (NHW) patients. Disease\u2010specific mortality was evaluated using Cox proportional hazards models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 3400 patients were identified, of which 569 (16.7%) were NHB and 2831 (83.3%) were NHW. Compared with NHW patients, NHB patients had more positive lymph nodes (7.6% vs. 3.9% <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). In addition, NHB women were more likely to undergo axillary lymph node dissection (6.0% vs. 3.8%, <jats:italic>p<\/jats:italic>\u2009=\u20090.044) and receive chemotherapy (11.8% vs. 7.2%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). There were no racial differences in breast surgery type (<jats:italic>p<\/jats:italic>\u2009=\u20090.168), reconstructive surgery (<jats:italic>p<\/jats:italic>\u2009=\u20090.362), or radiation therapy (<jats:italic>p<\/jats:italic>\u2009=\u20090.342). Overall, NHB patients had worse disease\u2010specific mortality (adjusted hazard ratio 2.13, 95% confidence interval [CI]: 1.10\u20134.14) with mortality risks diverging from NHW women after 3 years (6 years rate ratio [RR] 2.12, 95% CI: 1.13\u20134.34; 9 years RR 2.32, 95% CI: 1.24\u20134.35).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>NHB women with DCIS\u2010MI present with higher nodal disease burden and experience worse disease\u2010specific mortality than NHW women.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jso.27625","type":"journal-article","created":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T16:54:05Z","timestamp":1713718445000},"page":"1179-1186","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Racial disparities in disease\u2010specific mortality and surgical management of patients with ductal carcinoma in situ with microinvasion"],"prefix":"10.1002","volume":"129","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4356-5522","authenticated-orcid":false,"given":"J. C.","family":"Chen","sequence":"first","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery The Ohio State University Wexner Medical Center and James Cancer Hospital Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demond","family":"Handley","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, College of Medicine The Ohio State University Columbus Ohio USA"},{"name":"Secondary Data Core, Center for Biostatistics, College of Medicine The Ohio State University Columbus USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed I.","family":"Elsaid","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, College of Medicine The Ohio State University Columbus Ohio USA"},{"name":"Secondary Data Core, Center for Biostatistics, College of Medicine The Ohio State University Columbus USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James L.","family":"Fisher","sequence":"additional","affiliation":[{"name":"The Ohio State University College of Medicine Columbus Ohio USA"},{"name":"James Cancer Hospital and Solove Research Institute Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicci","family":"Owusu\u2010Brackett","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery The Ohio State University Wexner Medical Center and James Cancer Hospital Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lovette","family":"Azap","sequence":"additional","affiliation":[{"name":"The Ohio State University College of Medicine Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oindrila","family":"Bhattacharyya","sequence":"additional","affiliation":[{"name":"James Comprehensive Cancer Center The Ohio State University Columbus Ohio USA"},{"name":"The William Tierney Center for Health Services Research, Regenstrief Institute, Inc Indianapolis Indiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7994-9870","authenticated-orcid":false,"given":"Timothy M.","family":"Pawlik","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery The Ohio State University Wexner Medical Center and James Cancer Hospital Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7024-7533","authenticated-orcid":false,"given":"William E.","family":"Carson","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery The Ohio State University Wexner Medical Center and James Cancer Hospital Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5330-7247","authenticated-orcid":false,"given":"Samilia","family":"Obeng\u2010Gyasi","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery The Ohio State University Wexner Medical Center and James Cancer Hospital Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300060520969304"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(92)90900-3"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10451"},{"key":"e_1_2_8_5_1","volume-title":"NCCN Clinical Practice Guidelines in Oncology: Breast Cancer (Version 4.2022)","author":"National Comprehensive Cancer Network","year":"2022"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.11079"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2021.101557"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep42045"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2020.576964"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S341422"},{"key":"e_1_2_8_11_1","unstructured":"National Cancer Institute D Surveillance Research Program. 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